Key Insights

Highlights

Success Rate

76% trial completion

Published Results

84 trials with published results (20%)

Research Maturity

188 completed trials (44% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

14.3%

61 terminated out of 426 trials

Success Rate

75.5%

-11.0% vs benchmark

Late-Stage Pipeline

4%

17 trials in Phase 3/4

Results Transparency

45%

84 of 188 completed with results

Key Signals

84 with results76% success61 terminated

Data Visualizations

Phase Distribution

373Total
Not Applicable (38)
Early P 1 (19)
P 1 (171)
P 2 (128)
P 3 (17)

Trial Status

Completed188
Terminated61
Recruiting57
Unknown53
Active Not Recruiting32
Withdrawn20

Trial Success Rate

75.5%

Benchmark: 86.5%

Based on 188 completed trials

Clinical Trials (426)

Showing 20 of 20 trials
NCT07416188Phase 1Not Yet Recruiting

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

NCT05708352Phase 2RecruitingPrimary

A Phase 2 Study of the Ketogenic Diet vs Standard Anti-cancer Diet Guidance for Patients With Glioblastoma in Combination With Standard-of-care Treatment

NCT02331498Phase 1Active Not RecruitingPrimary

Phase I/II Study of Pazopanib+ Temozolomide in Patients With Newly Diagnosed Glioblastoma Multiforme

NCT05303467Phase 1RecruitingPrimary

A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM

NCT06814496Phase 1Recruiting

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

NCT06039709Phase 1Recruiting

Sonodynamic Therapy in Patients With Recurrent GBM

NCT07553520Not ApplicableWithdrawnPrimary

Dietary Cysteine and Methionine Deprivation (CMD) in Glioma Patients

NCT03961971Phase 1Active Not RecruitingPrimary

Trial of Anti-Tim-3 in Combination With Anti-PD-1 and SRS in Recurrent GBM

NCT05934630Terminated

Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors

NCT05843253Phase 2Recruiting

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

NCT05366179Phase 1RecruitingPrimary

Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc

NCT06466031Not ApplicableRecruitingPrimary

Application of FET-PET in Fusion With MRI in the Treatment of Glioblastoma Multiforme [TYR-GLIO]

NCT00083512RecruitingPrimary

Collection of Blood and Urine Samples in Patients Receiving Radiation Therapy for Glioblastoma Multiforme

NCT03911388Phase 1Recruiting

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

NCT04528680Phase 1Active Not Recruiting

Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent Glioblastoma

NCT04446416Not ApplicableCompletedPrimary

Efficacy and Safety of NaviFUS System add-on Bevacizumab (BEV) in Recurrent GBM Patients

NCT06496971Phase 3RecruitingPrimary

A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients

NCT06329570Phase 1RecruitingPrimary

Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM)

NCT05839379Recruiting

Targeted Pediatric High-Grade Glioma Therapy

NCT03596086Phase 1RecruitingPrimary

HSV-tk + Valacyclovir + SBRT + Chemotherapy for Recurrent GBM

Scroll to load more

Research Network

Activity Timeline