Key Insights

Highlights

Success Rate

72% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

10.8%

8 terminated out of 74 trials

Success Rate

72.4%

-14.1% vs benchmark

Late-Stage Pipeline

7%

5 trials in Phase 3/4

Results Transparency

48%

10 of 21 completed with results

Key Signals

10 with results72% success

Data Visualizations

Phase Distribution

69Total
Not Applicable (8)
Early P 1 (7)
P 1 (28)
P 2 (21)
P 3 (5)

Trial Status

Completed21
Recruiting16
Unknown12
Active Not Recruiting8
Terminated8
Not Yet Recruiting5

Trial Success Rate

72.4%

Benchmark: 86.5%

Based on 21 completed trials

Clinical Trials (74)

Showing 20 of 20 trials
NCT07416188Phase 1Not Yet Recruiting

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

NCT03451799Phase 1CompletedPrimary

Ketogenic Diet in Combination With Standard-of-care Radiation and Temozolomide for Patients With Glioblastoma

NCT07326566Phase 2Recruiting

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

NCT04528680Phase 1Active Not Recruiting

Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent Glioblastoma

NCT06388733Phase 3Recruiting

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

NCT07225621Phase 2Recruiting

Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma

NCT05086497Not ApplicableRecruitingPrimary

WBSI Guided Personalized Delivery of TTFields

NCT05076513Early Phase 1Active Not Recruiting

Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma

NCT04391595Early Phase 1Completed

LY3214996 Plus Abemaciclib in Recurrent Glioblastoma Patients

NCT07384884Not ApplicableNot Yet Recruiting

Surgery and Laser Interstitial Thermal Therapy for Bilateral Glioblastomas

NCT04606316Phase 1Active Not Recruiting

Surgical Nivolumab And Ipilimumab For Recurrent GBM

NCT04478279Phase 1Active Not Recruiting

A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors

NCT07387666Early Phase 1Not Yet Recruiting

Imaging Acetadote Metabolism in Glioblastoma

NCT04221503Phase 2Active Not Recruiting

Niraparib/TTFields in GBM

NCT05686798Phase 1Recruiting

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

NCT07274787Not ApplicableNot Yet RecruitingPrimary

Safety And Effectiveness Of NaviFUS System With Bevacizumab In Recurrent Glioblastoma

NCT06806228Phase 1Suspended

Phase I Pilot Study to Evaluate the Anti-glioblastoma Effect of S-Gboxin in Standard Treatment of Glioblastoma/Diffuse Midline Glioma and Response to Treatment (Regardless of Mutation Status)

NCT05902169Phase 3Active Not Recruiting

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM

NCT06855628Phase 2Suspended

Assessment of Novel Metabolic Imaging Modalities as A Predictor Of Therapeutic EfficacyiIn Glioblastoma (GBM)

NCT04424966Early Phase 1Terminated

Infigratinib in Recurrent High-Grade Glioma Patients

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