Key Insights

Highlights

Success Rate

74% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

10.7%

8 terminated out of 75 trials

Success Rate

74.2%

-12.4% vs benchmark

Late-Stage Pipeline

7%

5 trials in Phase 3/4

Results Transparency

43%

10 of 23 completed with results

Key Signals

10 with results74% success

Data Visualizations

Phase Distribution

70Total
Not Applicable (8)
Early P 1 (7)
P 1 (28)
P 2 (22)
P 3 (5)

Trial Status

Completed23
Recruiting18
Unknown12
Active Not Recruiting8
Terminated8
Not Yet Recruiting3

Trial Success Rate

74.2%

Benchmark: 86.6%

Based on 23 completed trials

Clinical Trials (75)

Showing 20 of 20 trials
NCT06855628Phase 2Completed

Assessment of Novel Metabolic Imaging Modalities as A Predictor Of Therapeutic EfficacyiIn Glioblastoma (GBM)

NCT05902169Phase 3Recruiting

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM

NCT07416188Phase 1Recruiting

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

NCT07326566Phase 2Recruiting

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

NCT04115761Phase 2RecruitingPrimary

Evaluate the Efficacy and Safety of ADCV01 as an Add-On Treatment for Primary Glioblastoma Multiforme (GBM) Patients

NCT07821112Phase 2Not Yet Recruiting

Phase II Elderly/Frail Pts With Newly Diagnosed or Recurrent Malignant Glioma Treated With Cesium-131 GammaTile®

NCT02974738Phase 1Active Not Recruiting

A Trial of Belzutifan (PT2977, MK-6482) Tablets In Patients With Advanced Solid Tumors (MK-6482-001)

NCT07384884Not ApplicableRecruiting

Surgery and Laser Interstitial Thermal Therapy for Bilateral Glioblastomas

NCT05086497Not ApplicableRecruitingPrimary

WBSI Guided Personalized Delivery of TTFields

NCT07225621Phase 2Recruiting

Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma

NCT06388733Phase 3Active Not Recruiting

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

NCT07387666Early Phase 1Recruiting

Imaging Acetadote Metabolism in Glioblastoma

NCT07274787Not ApplicableNot Yet RecruitingPrimary

Safety And Effectiveness Of NaviFUS System With Bevacizumab In Recurrent Glioblastoma

NCT06806228Phase 1Suspended

Phase I Pilot Study to Evaluate the Anti-glioblastoma Effect of S-Gboxin in Standard Treatment of Glioblastoma/Diffuse Midline Glioma and Response to Treatment (Regardless of Mutation Status)

NCT02861898Phase 1Recruiting

Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma

NCT04222309Phase 1Suspended

Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM)

NCT03630289Not ApplicableCompleted

Surgical Tissue Flap to Bypass the Blood Brain Barrier in GBM

NCT05271240Phase 3Recruiting

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

NCT05954858Not ApplicableRecruiting

Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma

NCT05979064Not ApplicableRecruiting

Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)

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