Key Insights

Highlights

Success Rate

73% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

10.8%

8 terminated out of 74 trials

Success Rate

73.3%

-13.2% vs benchmark

Late-Stage Pipeline

7%

5 trials in Phase 3/4

Results Transparency

45%

10 of 22 completed with results

Key Signals

10 with results73% success

Data Visualizations

Phase Distribution

69Total
Not Applicable (8)
Early P 1 (7)
P 1 (28)
P 2 (21)
P 3 (5)

Trial Status

Completed22
Recruiting17
Unknown12
Terminated8
Active Not Recruiting7
Not Yet Recruiting4

Trial Success Rate

73.3%

Benchmark: 86.5%

Based on 22 completed trials

Clinical Trials (74)

Showing 20 of 20 trials
NCT07416188Phase 1Recruiting

Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

NCT07326566Phase 2Recruiting

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

NCT05902169Phase 3Recruiting

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM

NCT07225621Phase 2Recruiting

Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma

NCT07274787Not ApplicableNot Yet RecruitingPrimary

Safety And Effectiveness Of NaviFUS System With Bevacizumab In Recurrent Glioblastoma

NCT06806228Phase 1Suspended

Phase I Pilot Study to Evaluate the Anti-glioblastoma Effect of S-Gboxin in Standard Treatment of Glioblastoma/Diffuse Midline Glioma and Response to Treatment (Regardless of Mutation Status)

NCT02861898Phase 1Recruiting

Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma

NCT04222309Phase 1Suspended

Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM)

NCT03630289Not ApplicableCompleted

Surgical Tissue Flap to Bypass the Blood Brain Barrier in GBM

NCT05954858Not ApplicableRecruiting

Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma

NCT05979064Not ApplicableRecruiting

Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)

NCT05271240Phase 3Recruiting

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

NCT05933265Phase 1Active Not Recruiting

Study of LP-184 in Patients With Advanced Solid Tumors

NCT06039709Phase 1Recruiting

Sonodynamic Therapy in Patients With Recurrent GBM

NCT03451799Phase 1CompletedPrimary

Ketogenic Diet in Combination With Standard-of-care Radiation and Temozolomide for Patients With Glioblastoma

NCT04528680Phase 1Active Not Recruiting

Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent Glioblastoma

NCT06388733Phase 3Recruiting

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

NCT05086497Not ApplicableRecruitingPrimary

WBSI Guided Personalized Delivery of TTFields

NCT05076513Early Phase 1Active Not Recruiting

Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Glioma

NCT04391595Early Phase 1Completed

LY3214996 Plus Abemaciclib in Recurrent Glioblastoma Patients

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