Key Insights

Highlights

Success Rate

72% trial completion

Published Results

19 trials with published results (22%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

13.6%

12 terminated out of 88 trials

Success Rate

72.1%

-14.4% vs benchmark

Late-Stage Pipeline

6%

5 trials in Phase 3/4

Results Transparency

61%

19 of 31 completed with results

Key Signals

19 with results72% success12 terminated

Data Visualizations

Phase Distribution

78Total
Not Applicable (13)
P 1 (27)
P 2 (33)
P 3 (5)

Trial Status

Completed31
Recruiting19
Active Not Recruiting13
Terminated12
Unknown5
Not Yet Recruiting4

Trial Success Rate

72.1%

Benchmark: 86.5%

Based on 31 completed trials

Clinical Trials (88)

Showing 20 of 20 trials
NCT06239194Phase 1Recruiting

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

NCT03610711Phase 1Active Not RecruitingPrimary

REACTION (Radiation Enhanced Assessment of Combination Therapies in Immuno-ONcology) - Nivolumab or Nivolumab in Combination With Other Immuno-oncology (IO) Agents After Targeted Systemic Radiation in Patients With Advanced Esophagogastric Cancer

NCT05379972Phase 2Active Not Recruiting

Study of SBRT/Olaparib Followed by Pembrolizumab/Olaparib in Gastric Cancers

NCT06257264Phase 1Recruiting

A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors

NCT04544046Not ApplicableActive Not Recruiting

Supportive Oncology Care At Home RCT

NCT06695845Phase 2Recruiting

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

NCT03798626Phase 1Completed

Gevokizumab With Standard of Care Anti-cancer Therapies for Metastatic Colorectal, Gastroesophageal, and Renal Cancers

NCT06497569Not ApplicableRecruitingPrimary

Support Through Remote Observation and Nutrition Guidance Program for Individuals With Gastroesophageal Cancer

NCT03044613Phase 1Active Not Recruiting

Nivolumab +/- Relatlimab Prior to Chemoradiation With II/III Gastro/Esophageal Cancer

NCT07477444Phase 1Not Yet RecruitingPrimary

Perioperative Zanidatamab and Chemotherapy for HER2 Positive Gastroesophageal Cancer

NCT07481357Phase 1Not Yet Recruiting

A First-In-Human Phase I/IIa Study to Evaluate DA 3501 in Patients With Advanced Gastric or Gastro-esophageal Junction Adenocarcinoma and Pancreatic Ductal Adenocarcinoma

NCT06356311Phase 3Active Not RecruitingPrimary

A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015)

NCT06171789Phase 1Terminated

PRO1107 in Patients With Advanced Solid Tumors

NCT05338060CompletedPrimary

A Systems Approach to Immunotherapy Biomarker Identification Within the Postoperative Wound-Healing Microenvironment in Patients With Gastroesophageal Cancer

NCT06109467Phase 2RecruitingPrimary

Neratinib In Combination With Chemotherapy/Trastuzumab/Pembrolizumab In HER2 Gastroesophageal Cancer

NCT06242470Phase 1Recruiting

A Study of MGC026 in Participants With Advanced Solid Tumors

NCT05205343Recruiting

Trans-Pacific Multicenter Collaborative Study of Minimally Invasive Proximal Versus Total Gastrectomy for Proximal Gastric and Gastroesophageal Junction Cancers

NCT06283238WithdrawnPrimary

Biobanking Upper Gastrointestinal Tumors to Evaluate Response (BURGER With BACON)

NCT06468280Phase 2Recruiting

Synergistic Effects of PD-1 Antibody and Chemotherapy/Targeted Therapy Followed by Surgery-centric Local Treatment in Patients With Limited-metastatic Gastric Cancer

NCT07318051Recruiting

Sample Collection for Ongoing Research and Product Evaluation Study

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