Key Insights

Highlights

Success Rate

63% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

10.3%

3 terminated out of 29 trials

Success Rate

62.5%

-24.0% vs benchmark

Late-Stage Pipeline

3%

1 trials in Phase 3/4

Results Transparency

60%

3 of 5 completed with results

Key Signals

3 with results63% success

Data Visualizations

Phase Distribution

28Total
Early P 1 (1)
P 1 (13)
P 2 (13)
P 3 (1)

Trial Status

Recruiting13
Completed5
Not Yet Recruiting4
Active Not Recruiting3
Terminated3
Withdrawn1

Trial Success Rate

62.5%

Benchmark: 86.5%

Based on 5 completed trials

Clinical Trials (29)

Showing 20 of 20 trials
NCT06469944Phase 1Recruiting

Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)

NCT06445972Phase 1Recruiting

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

NCT07529808Phase 1Not Yet Recruiting

Phase 1/2 Study of BHB810 in Advanced Gastric and GEJ Adenocarcinoma

NCT07544589Phase 1Recruiting

A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

NCT07069712Phase 2RecruitingPrimary

A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma

NCT05152147Phase 3Active Not Recruiting

A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers

NCT07223424Phase 2Recruiting

Patient Preference for Subcutaneous vs. Intravenous Immune Therapy

NCT05733689Phase 1RecruitingPrimary

Response Adapted Neoadjuvant Therapy in Gastroesophageal Cancers (RANT-GC Trial)

NCT07282912Phase 2Recruiting

Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With Metastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid (ctDNA) Levels

NCT07176312Phase 2RecruitingPrimary

Zanidatamab in Combination With Pembrolizumab and Chemotherapy in HER2 and PD-L1 Positive Metastatic Gastroesophageal Adenocarcinoma (GEA) Patients

NCT06043427Phase 2RecruitingPrimary

Paclitaxel and Ramucirumab +/- Zanidatamab in HER2 Postive Advanced Gastroesophageal Adenocarcinoma

NCT07266025Phase 2Not Yet Recruiting

Adebrelimab Combined With Induction Chemotherapy or SHR-8068 for Mismatch Repair-Deficient/Microsatellite Instability-High (dMMR/MSI-H) Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma:A Randomized, Non-comparative Phase 2 Study

NCT06921837Phase 1Recruiting

A First-in-Human Study Using BDC-4182 as a Single Agent in Advanced Gastric and Gastroesophageal Cancer

NCT07290985Phase 2Not Yet RecruitingPrimary

AACR Adaptive Biomarker-Driven Organ Preservation Trial in Gastroesophageal Adenocarcinomas

NCT06529822Phase 1Recruiting

Personalized Cancer Vaccine (PCV) Strategy in Patients With Solid Tumors and Molecular Residual Disease

NCT05977322Phase 1Terminated

A Phase I Study of [177Lu]Lu-FF58 in Patients With Advanced Solid Tumors.

NCT05029882Phase 1Active Not Recruiting

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Advanced Solid Tumors Receiving Intravenous (IV) ABBV-400 as Monotherapy and in Combination With IV Bevacizumab

NCT04712721Early Phase 1Terminated

Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins.

NCT06767800Phase 2RecruitingPrimary

A Clinical Trial Evaluating TQB2102 for Injection in Combination With Behmosubaisumab/Payamprolizumab With or Without Chemotherapy in Unresectable Locally Advanced, Recurrent, or Metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Gastroesophageal Adenocarcinoma

NCT04021108Phase 2Active Not RecruitingPrimary

Phase II Study of Short Course FOLFOX Chemotherapy With Either Nivolumab or Nivolumab + Radiation in the First Line Treatment of Metastatic or Unresectable Gastroesophageal Cancers (BMS Protocol CA209-76L)

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