Key Insights

Highlights

Success Rate

100% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

0.0%

0 terminated out of 24 trials

Success Rate

100.0%

+13.4% vs benchmark

Late-Stage Pipeline

8%

2 trials in Phase 3/4

Results Transparency

25%

2 of 8 completed with results

Key Signals

2 with results100% success

Data Visualizations

Phase Distribution

22Total
P 1 (7)
P 2 (13)
P 3 (2)

Trial Status

Not Yet Recruiting9
Completed8
Recruiting4
Unknown3

Trial Success Rate

100.0%

Benchmark: 86.6%

Based on 8 completed trials

Clinical Trials (24)

Showing 20 of 20 trials
NCT05482893Phase 1RecruitingPrimary

Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or Targeted Therapy and/or ICI, for the Treatment of Patients With Advanced Gastrointestinal Cancers, Including Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)

NCT07772557Phase 2Not Yet RecruitingPrimary

Adjuvant Therapy for Potentially Immunotherapy-Responsive Gastric or Gastroesophageal Junction Adenocarcinoma

NCT07727993Phase 1Not Yet RecruitingPrimary

Neoadjuvant Propranolol Plus SOX and Toripalimab for Locally Advanced Gastric/GEJ Adenocarcinoma

NCT07716111Phase 2Not Yet RecruitingPrimary

Neoadjuvant SHR-A1811 and SHR-A1701 ± Pertuzumab for Potentially Immunotherapy-Sensitive GC or GEJ Adenocarcinoma

NCT07716449Phase 3Not Yet RecruitingPrimary

QLS31905 in Combination With CAPOX Versus Sintilimab in Combination With CAPOX as First-line Treatment in Patients With GC/GEJ

NCT05941481Phase 2CompletedPrimary

Neoadjuvant Chemo-hypoRT Plus PD-1 Antibody (Tislelizumab) in Resectable LA-G/GEJ

NCT07581574Phase 1Not Yet RecruitingPrimary

Neoadjuvant SHR-A1811 and SHR-A1701 for Potentially Immunotherapy-Sensitive GC or GEJ Adenocarcinoma

NCT07408609Phase 2Not Yet RecruitingPrimary

Perioperative Chemotherapy With Low-Dose Radiotherapy and Tislelizumab for Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

NCT07400315Phase 2Not Yet RecruitingPrimary

First-line Treatment of Gastric or Gastroesophageal Junction Adenocarcinoma With Dual Immunotherapy Combined With Chemotherapy

NCT06841679Phase 2RecruitingPrimary

Utidelone Capsule Combined With Fluoropyrimidine- and Platinum-containing Therapy in First-line Treatment of Patients With Gastric or Gastroesophageal Junction Adenocarcinoma

NCT07115485Phase 2RecruitingPrimary

Phase II, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of HLX43 (an Anti-PD-L1 ADC) in Subjects With Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

NCT07151209Phase 2Not Yet RecruitingPrimary

Immunotherapy Combined With Anti-angiogenic Therapy and Chemotherapy for Potentially Resectable MSI-H, dMMR Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

NCT07091227Phase 2Not Yet RecruitingPrimary

Efficacy and Safety of AK112 Combined Chemotherapy as Neoadjuvant Treatment for Signet Ring Cell-containing G/GEJ Adenocarcinoma

NCT06440811Completed

Efficacy and Safety of Neoadjuvant Nivolumab Plus SOX Versus Nivolumab Plus FLOT in Patients With HER2-negative Gastric and Gastroesophageal Junction Adenocarcinoma

NCT03777657Phase 3CompletedPrimary

Tislelizumab in Combination With Chemotherapy as First-Line Treatment in Adults With Inoperable, Locally Advanced or Metastatic Gastric, or Gastroesophageal Junction Carcinoma

NCT06587425Phase 2RecruitingPrimary

The Efficacy and Safety of LM-302 in Combination With Candonilimab and Capecitabine for First-Line Treatment in Patients With Unresectable Advanced, Recurrent, or Metastatic CLDN18.2-Positive Gastric or Gastroesophageal Junction Adenocarcinoma

NCT03752398Phase 1Completed

A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3)

NCT05994456Phase 2UnknownPrimary

Neoadjuvant Toripalimab for dMMR/MSI-H Gastric Cancer

NCT03849469Phase 1Completed

A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors

NCT03517488Phase 1Completed

A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors

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