Key Insights

Highlights

Success Rate

88% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

6.0%

3 terminated out of 50 trials

Success Rate

88.5%

+2.0% vs benchmark

Late-Stage Pipeline

12%

6 trials in Phase 3/4

Results Transparency

22%

5 of 23 completed with results

Key Signals

5 with results88% success

Data Visualizations

Phase Distribution

39Total
Not Applicable (19)
Early P 1 (3)
P 1 (4)
P 2 (7)
P 3 (3)
P 4 (3)

Trial Status

Completed23
Recruiting14
Unknown7
Terminated3
Withdrawn2
Not Yet Recruiting1

Trial Success Rate

88.5%

Benchmark: 86.5%

Based on 23 completed trials

Clinical Trials (50)

Showing 20 of 20 trials
NCT04417959Not ApplicableCompletedPrimary

A Comparison of Visual Functions and Side-effects After DSAEK or DMEK for Fuchs' Endothelial Dystrophy

NCT05134480Not ApplicableCompleted

Impact of Donor Diabetes on DMEK Success and Endothelial Cell Loss

NCT06261346Not ApplicableRecruitingPrimary

Plasma Rich in Growth Factors in Corneal Endothelial Transplantation

NCT07325097Phase 1Recruiting

PVEK Corneal Implant For Treatment of Corneal Edema

NCT05275972Phase 3Recruiting

Descemet Endothelial Thickness Comparison Trial II

NCT05636579Phase 1Recruiting

Study to Assess Safety and Tolerability of Multiple Doses of EO2002

NCT05436665Not ApplicableRecruiting

The Belgian Endothelial Surgical Transplant of the Cornea

NCT02118922Recruiting

A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal Ectasia

NCT05716945Phase 4Recruiting

The OPTIMISE Study

NCT04319848Phase 1Recruiting

Safety and Efficacy of Tissue Engineered Endothelial Keratoplasty

NCT02423213Recruiting

DISCOVER Study: Microscope-integrated Intraoperative OCT Study

NCT06914817Not ApplicableNot Yet Recruiting

Brillouin Microscopy Used to Evaluate Corneal Mechanical Properties

NCT06881771Recruiting

FECD-TRACE: Fuchs' Endothelial Corneal Dystrophy TRAjectory and Correlation With Genotype in the United Kingdom

NCT06048380Phase 3RecruitingPrimary

The Effects of Ripasudil in Patients With FED Undergoing Femtosecond Laser Assisted Cataract Surgery

NCT06652321Not ApplicableRecruiting

Endothelial Side Up Inverted Femtosecond Laser Assisted DSAEK

NCT02423161Completed

PIONEER: Intraoperative and Perioperative OCT Study

NCT03813056Phase 2RecruitingPrimary

Ripasudil for Enhanced Corneal Clearing Following Descemet Membrane Endothelial Keratoplasty in Fuchs' Dystrophy

NCT04752020Early Phase 1CompletedPrimary

Netarsudil Use After Descemtorhexis Without Endothelial Keratoplasty

NCT04676737Phase 2CompletedPrimary

TTHX1114(NM141) in Combination With DWEK/DSO

NCT05399095Not ApplicableCompletedPrimary

Supine Positioning for Graft Attachment After Descemet Membrane Endothelial Keratoplasty

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