Key Insights

Highlights

Success Rate

50% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

12.5%

2 terminated out of 16 trials

Success Rate

50.0%

-36.5% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

50%

1 of 2 completed with results

Key Signals

1 with results50% success

Data Visualizations

Phase Distribution

9Total
Not Applicable (4)
P 1 (4)
P 2 (1)

Trial Status

Recruiting8
Terminated2
Active Not Recruiting2
Completed2
Not Yet Recruiting1
Enrolling By Invitation1

Trial Success Rate

50.0%

Benchmark: 86.5%

Based on 2 completed trials

Clinical Trials (16)

Showing 16 of 16 trials
NCT06064890Phase 1Recruiting

A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)

NCT06856850Recruiting

Disease Biosignatures in ALS/FTD Spectrum: New Impactful Biological Perspectives Beyond Clinical Approaches

NCT05956834Active Not Recruiting

A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration (FTLD) Syndromes

NCT04060082Completed

Voices Of Individuals: Challenges and Experiences Of bvFTD

NCT07316413Not ApplicableRecruiting

Repetitive Transcranial Magnetic Stimulation in Frontotemporal Lobar Degeneration

NCT04747431Phase 1Recruiting

A Study of PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 Genes

NCT07235111Recruiting

Omics Sciences for the Identification of Pathogenetic Mechanisms and Biomarkers in Neurodegenerative Diseases

NCT04680130Enrolling By Invitation

Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related Disorders

NCT04516499Active Not Recruiting

Neurofilament Surveillance Project (NSP)

NCT07100470Not ApplicableNot Yet RecruitingPrimary

Metabolic Characterization of Alzheimer's Disease and Frontotemporal Dementia by 23Na-MRI and FDG-PET

NCT04946916Not ApplicableRecruiting

Neurofilament Light Chains and Cognitive Impairment in Chronic Psychiatric Disease

NCT05742698Phase 2Recruiting

Nabilone for Agitation in Frontotemporal Dementia

NCT06595212Recruiting

Genetics and Environment iNtersection In the ALS-FTD Spectrum: an Italian Twins Cohort studY With a Multi-Omics Approach

NCT02606422Not ApplicableCompleted

tDCS Intervention in Primary Progressive Aphasia

NCT04931862Phase 1Terminated

Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) or Frontotemporal Dementia (FTD)

NCT05683860Phase 1Terminated

Open-label Extension (OLE) Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) and/or Frontotemporal Dementia (FTD)

Showing all 16 trials

Research Network

Activity Timeline