Key Insights

Highlights

Success Rate

88% trial completion (above average)

Published Results

46 trials with published results (22%)

Research Maturity

106 completed trials (50% of total)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 27/100

Termination Rate

6.6%

14 terminated out of 213 trials

Success Rate

88.3%

+1.8% vs benchmark

Late-Stage Pipeline

18%

39 trials in Phase 3/4

Results Transparency

43%

46 of 106 completed with results

Key Signals

46 with results88% success14 terminated

Data Visualizations

Phase Distribution

103Total
Not Applicable (17)
Early P 1 (1)
P 1 (23)
P 2 (23)
P 3 (27)
P 4 (12)

Trial Status

Completed106
Recruiting35
Unknown30
Terminated14
Active Not Recruiting11
Withdrawn8

Trial Success Rate

88.3%

Benchmark: 86.5%

Based on 106 completed trials

Clinical Trials (213)

Showing 20 of 20 trials
NCT05368038Enrolling By Invitation

ScreenPlus: A Comprehensive, Flexible, Multi-disorder Newborn Screening Program

NCT06906367RecruitingPrimary

A Study of Patients With Fabry Disease (US Specific)

NCT07109375RecruitingPrimary

Observational Study on Long-term Use of Pegunigalsidase Alfa in Fabry Patients in a Real-world Setting

NCT04020055Phase 3Active Not RecruitingPrimary

A Study to Evaluate Migalastat in Fabry Subjects With Amenable GLA Variant and Renal Disease

NCT03737214Phase 3Active Not RecruitingPrimary

A Study to Evaluate the Long-term Safety and Tolerability of Lucerastat in Adult Subjects With Fabry Disease

NCT07575347Recruiting

Periodontal Disease in Rare Renal Disorders (PERIO-RA-RE)

NCT06904261Phase 3RecruitingPrimary

A Study of Migalastat in Pediatric Subjects (2 to <12 Yrs) With Fabry Disease and Amenable GLA Variants

NCT05280548Phase 3Active Not RecruitingPrimary

A Study to Evaluate the Effect of Venglustat Tablets on Left Ventricular Mass Index in Male and Female Adult Participants With Fabry Disease

NCT00196742RecruitingPrimary

Fabry Disease Registry & Pregnancy Sub-registry

NCT04073888Not ApplicableTerminatedPrimary

Study of the Spermatic Characteristics of Patients With Fabry Disease

NCT05923788Not ApplicableCompletedPrimary

T1 Mapping in Fabry Disease

NCT03614234Phase 3CompletedPrimary

Open Label Extension of 2 mg/kg Pegunigalsidase Alfa (PRX-102) Every 4 Weeks in Adult Fabry Disease Patients

NCT06052800Active Not RecruitingPrimary

Agalsidase Beta Long-Term Treatment Outcome for Fabry Disease Patients With IVS4 Mutation in Taiwan

NCT07560956Not Yet RecruitingPrimary

Quality of Life in Adults With Untreated Fabry Disease in Sweden (QoLUF)

NCT06095713Active Not RecruitingPrimary

German Observational Multicenter Study of Patients With Fabry Disease Under Enzyme Replacement Therapy With Pegunigalsidase-alfa

NCT04856059Not ApplicableRecruitingPrimary

Fabry Cardiomyopathy: Identification of Early Myocardial Structural and Tissue Abnormalities Using Multiparametric MRI

NCT04046224Phase 1CompletedPrimary

Dose-Ranging Study of ST-920, an AAV2/6 Human Alpha Galactosidase A Gene Therapy in Subjects With Fabry Disease (STAAR)

NCT07506083Active Not RecruitingPrimary

Natural History in Fabry Disease With IVS4+919G>A Mutations

NCT07495410Not ApplicableEnrolling By InvitationPrimary

Anderson-Fabry Disease Fitness Improvement Training: A-FAD-FIT

NCT03566017Phase 3CompletedPrimary

Open Label Extension Study of 1 mg/kg Pegunigalsidase Alfa Every 2 Weeks in Patients With Fabry Disease

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