Key Insights

Highlights

Success Rate

76% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 39/100

Termination Rate

9.1%

4 terminated out of 44 trials

Success Rate

76.5%

-10.0% vs benchmark

Late-Stage Pipeline

18%

8 trials in Phase 3/4

Results Transparency

62%

8 of 13 completed with results

Key Signals

8 with results76% success

Data Visualizations

Phase Distribution

41Total
Not Applicable (1)
P 1 (12)
P 2 (20)
P 3 (7)
P 4 (1)

Trial Status

Completed13
Unknown13
Not Yet Recruiting7
Terminated4
Active Not Recruiting3
Recruiting2

Trial Success Rate

76.5%

Benchmark: 86.5%

Based on 13 completed trials

Clinical Trials (44)

Showing 20 of 20 trials
NCT07509034Phase 1Not Yet RecruitingPrimary

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

NCT07535359Unknown

Medical Access Program for Ifinatamab Deruxtecan in 3L+ Pretreated Extensive-stage Small Cell Lung Cancer

NCT04702880Phase 2CompletedPrimary

A Study of BMS-986012 in Combination With Carboplatin, Etoposide, and Nivolumab as First-line Therapy in Extensive-stage Small Cell Lung Cancer

NCT07328490Phase 1WithdrawnPrimary

Bispecific T-Cell Engager Tarlatamab and TROP2 Targeted Antibody Drug Conjugate Sacituzumab Govitecan in Previously Treated Extensive-Stage Small Cell Lung Cancer and Extrapulmonary Neuroendocrine Cancer

NCT06646276Phase 3RecruitingPrimary

A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).

NCT07489339Not ApplicableCompleted

MDT-Based Nursing for Small Cell Lung Cancer During Chemo-Immunotherapy

NCT07388875Phase 2Not Yet RecruitingPrimary

Sacituzumab Tirumotecan Plus Anlotinib in Previously Treated ES-SCLC

NCT04373369Phase 2TerminatedPrimary

Vorolanib + Atezolizumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer

NCT04397003Phase 2Active Not RecruitingPrimary

Personalized Neoantigen Vaccine in Combination With Durvalumab (MEDI4736) in Extensive Stage Small Cell Lung Cancer

NCT05509699Phase 2CompletedPrimary

Surufatinib Plus Anti-PD-1/L1 as Maintenance Therapy in Extensive-Stage Small Cell Lung Cancer

NCT04774380Phase 3CompletedPrimary

Study of Durvalumab in Combination With Platinum and Etoposide for the First Line Treatment of Patients With Extensive-stage Small Cell Lung Cancer

NCT06931145Phase 4Not Yet RecruitingPrimary

Benmelstobart, Anlotinib and Chemotherapy as First-line Treatment for Extensive-stage Small-cell Lung Cancer

NCT04101357Phase 1Terminated

Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411

NCT03043599Phase 1Completed

Ipilimumab + Nivolumab w/Thoracic Radiotherapy for Extensive-Stage Small Cell Lung Cancer

NCT06719336Phase 3Not Yet RecruitingPrimary

Addition of Thoracic Consolidation Radiotherapy to the Maintenance Immunotherapy for ES-SCLC (STONE-001)

NCT06614621Phase 2Not Yet RecruitingPrimary

A Study of Adebelimab Combined With Chemotherapy as a First-line Treatment Sequential Treatment for Extensive-stage Small Cell Lung Cancer

NCT00791154Phase 1Terminated

QUILT-2.013: First-Line Treatment for Extensive Stage Small Cell Lung Cancer

NCT06554535Phase 2Not Yet RecruitingPrimary

Efficacy and Safety of Serplulimab With Chemotherapy and Aspirin in Untreated Extensive-Stage Small Cell Lung Cancer

NCT06479473Phase 1RecruitingPrimary

Radiotherapy to All Residual Lesions After Chemoimmunotherapy

NCT06497530Phase 2Not Yet RecruitingPrimary

Maintenance Lurbinectedin in Combination With Serplulimab for Patients With ES-SCLC

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