Key Insights

Highlights

Success Rate

80% trial completion

Published Results

13 trials with published results (27%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.2%

6 terminated out of 49 trials

Success Rate

80.0%

-6.5% vs benchmark

Late-Stage Pipeline

4%

2 trials in Phase 3/4

Results Transparency

54%

13 of 24 completed with results

Key Signals

13 with results80% success

Data Visualizations

Phase Distribution

46Total
Not Applicable (3)
P 1 (16)
P 2 (25)
P 3 (2)

Trial Status

Completed24
Unknown7
Terminated6
Recruiting6
Active Not Recruiting4
Not Yet Recruiting1

Trial Success Rate

80.0%

Benchmark: 86.5%

Based on 24 completed trials

Clinical Trials (49)

Showing 20 of 20 trials
NCT05903092Phase 2Recruiting

MOnaliZumab in Combination With durvAlumab (MEDI4736) for tRreatmenT of Small Cell Lung Cancer

NCT06897579Phase 2TerminatedPrimary

Carboplatin/Cisplatin + Etoposide + Benmelstobart Sequential Benmelstobart Combined With Anlotinib Versus Carboplatin/Cisplatin + Etoposide + Tislelizumab Sequential Tislelizumab in the Treatment of Extensive Stage Small Cell Lung Cancer

NCT06502977Phase 2Active Not RecruitingPrimary

Study Evaluating Tarlatamab in Chinese Participants With Advanced Small Cell Lung Cancer After Two or More Prior Lines of Treatment

NCT07037758Phase 1RecruitingPrimary

A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)

NCT05142696Phase 1Active Not RecruitingPrimary

A Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed ES-SCLC Patients in Combination With Carboplatin, Etoposide and Atezolizumab

NCT05361395Phase 1Active Not RecruitingPrimary

First-Line Tarlatamab in Combination With Carboplatin, Etoposide, and PD-L1 Inhibitor in Subjects With Extensive Stage Small Cell Lung Cancer (ES-SCLC)

NCT07107490Phase 1RecruitingPrimary

A PHASE I STUDY OF ALPS12 IN PATIENTS WITH EXTENSIVE STAGE SMALL CELL LUNG CANCER

NCT04699838Phase 2RecruitingPrimary

Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer

NCT04063163Phase 3CompletedPrimary

A Phase III Study to Investigate Efficacy and Safety of HLX10 + Chemotherapy in Patients With ES-SCLC

NCT06598306Phase 1RecruitingPrimary

Subcutaneous Tarlatamab in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-308)

NCT05468489Phase 3Active Not RecruitingPrimary

To Evaluate Efficacy and Safety of Serplulimab + Chemotherapy (Carboplatin- Etoposide) in US Patients With ES-SCLC

NCT06016270Phase 1TerminatedPrimary

A Study of hSTC810 in Combination With Paclitaxel in Relapsed or Refractory Extensive Stage Small Cell Lung Cancer

NCT06597513Phase 1Not Yet RecruitingPrimary

Auto-HSCT-Supported Dose-Dense Chemotherapy with Adebrelimab As First-Line Treatment for ES-SCLC

NCT06323265RecruitingPrimary

A Real-world Study of Adebrelimab Combined With Chemotherapy±Chest Radiotherapy in Patients With Extensive Stage Small Cell Lung Cancer

NCT00019006Phase 1Completed

Vaccine Therapy in Treating Patients With Colon, Pancreatic, or Lung Cancer

NCT00020202Phase 2CompletedPrimary

FR901228 in Treating Patients With Refractory or Progressive Small Cell Lung Cancer or Non-small Cell Lung Cancer

NCT00057837Phase 2CompletedPrimary

Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Extensive-Stage Small Cell Lung Cancer

NCT05896059Phase 2UnknownPrimary

A Study to Investigate the Efficacy and Safety of Tislelizumab Combined With Anlotinib as Maintenance Therapy for ES-SCLC

NCT04346914Phase 1UnknownPrimary

Study of ZKAB001 Combined With Carboplatin and Etoposide in the Extensive Small Cell Lung Cancer

NCT01935336Phase 2Completed

Study of Ponatinib in Patients With Lung Cancer Preselected Using Different Candidate Predictive Biomarkers

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