Key Insights

Highlights

Success Rate

72% trial completion

Published Results

21 trials with published results (51%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

19.5%

8 terminated out of 41 trials

Success Rate

72.4%

-14.1% vs benchmark

Late-Stage Pipeline

2%

1 trials in Phase 3/4

Results Transparency

100%

21 of 21 completed with results

Key Signals

21 with results72% success

Data Visualizations

Phase Distribution

38Total
Not Applicable (7)
Early P 1 (1)
P 1 (3)
P 2 (26)
P 3 (1)

Trial Status

Completed21
Terminated8
Active Not Recruiting5
Unknown3
Recruiting2
Withdrawn2

Trial Success Rate

72.4%

Benchmark: 86.5%

Based on 21 completed trials

Clinical Trials (41)

Showing 20 of 20 trials
NCT03962647Early Phase 1CompletedPrimary

A 2-Week Ketogenic Diet in Combination With Letrozole to Modulate PI3K Signaling in ER+ Breast Cancer

NCT03633331Phase 2CompletedPrimary

Palbociclib and Letrozole or Fulvestrant in Treating Patients With Estrogen Receptor Positive, HER2 Negative Metastatic Breast Cancer

NCT02957968Phase 2Active Not Recruiting

Neoadjuvant Pembrolizumab + Decitabine Followed by Std Neoadj Chemo for Locally Advanced HER2- Breast Ca

NCT01953588Phase 3Active Not RecruitingPrimary

Fulvestrant and/or Anastrozole in Treating Postmenopausal Patients With Stage II-III Breast Cancer Undergoing Surgery

NCT04597580Active Not Recruiting

Personalised Disease Monitoring in Metastatic Breast Cancer

NCT02186470Not ApplicableCompletedPrimary

Intensity Modulated Accelerated Partial Breast Irradiation Before Surgery in Treating Older Patients With Hormone Responsive Stage 0-I Breast Cancer

NCT06439693Phase 2Recruiting

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

NCT01824836Not ApplicableActive Not RecruitingPrimary

A Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms (AIMSS)

NCT04965688Phase 2Terminated

Biology Guided Therapy for Breast Cancer for ER Positive

NCT05020860Phase 2Recruiting

Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer

NCT01791478Phase 1Active Not RecruitingPrimary

BYL719 and Letrozole in Post-Menopausal Patients With Hormone Receptor-Positive Metastatic Breast Cancer

NCT03395899Phase 2Completed

Pre-operative Immunotherapy Combination Strategies in Breast Cancer

NCT03719495Completed

Evaluation of Endocrine Therapy Effects of Host Immunity in Early Stage Breast Cancer

NCT03285568Completed

Patterns of Prescribing and Monitoring of Palbociclib

NCT02235051Not ApplicableCompleted

Exercise Intervention in Preventing Breast Cancer Recurrence in Postmenopausal Breast Cancer Survivors

NCT00676663Phase 2Completed

Study to Evaluate Exemestane With and Without Entinostat (SNDX-275) in Treatment of Postmenopausal Women With Advanced Breast Cancer

NCT02269670Phase 2TerminatedPrimary

Phase II Study of Everolimus Beyond Progression

NCT04038489Phase 2Withdrawn

COX Inhibition and Biomarkers During Neoadjuvant Chemoendocrine Therapy for ER+, HER2- Stage I-III Breast Cancer

NCT05076695Phase 2UnknownPrimary

Neoadjuvant With Trastuzumab, Pyrotinib Plus Palbociclib and Fulvestrant in HER2-positive, ER-positive Breast Cancer

NCT01037790Phase 2Completed

Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer

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Research Network

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