Key Insights

Highlights

Success Rate

86% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

5.3%

6 terminated out of 114 trials

Success Rate

85.7%

-0.8% vs benchmark

Late-Stage Pipeline

4%

5 trials in Phase 3/4

Results Transparency

19%

7 of 36 completed with results

Key Signals

7 with results86% success

Data Visualizations

Phase Distribution

83Total
Not Applicable (30)
P 1 (25)
P 2 (23)
P 3 (5)

Trial Status

Completed36
Recruiting29
Unknown23
Active Not Recruiting8
Not Yet Recruiting8
Terminated6

Trial Success Rate

85.7%

Benchmark: 86.6%

Based on 36 completed trials

Clinical Trials (114)

Showing 20 of 20 trials
NCT05400122Phase 1Suspended

Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer

NCT07700420Phase 1Not Yet Recruiting

Perioperative FLOT(D) With Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy (PULSAR) in Esophageal Cancer

NCT04046575Phase 1Active Not RecruitingPrimary

Radiation Dose Intensification With Accelerated Hypofractionated Intensity Modulated Radiation Therapy and Concurrent Carboplatin and Paclitaxel for Inoperable Esophageal Cancer

NCT07063901RecruitingPrimary

Multimodal Deep Learning for Predicting Treatment Response to Neoadjuvant Chemoimmunotherapy in Esophageal Cancer

NCT05780684Not ApplicableRecruiting

Individualized Dose Escalation of 5-FU for Gastrointestinal Cancer

NCT01684904Not ApplicableRecruitingPrimary

Proton Therapy for Esophageal Cancer

NCT06097078Active Not Recruiting

Endoluminal Vacuum Therapy to Prevent Anastomotic Leakage After Esophagectomy Due to Esophageal Cancer

NCT07617246Phase 2RecruitingPrimary

The Efficacy and Safety of Fosrolapitant and Palonosetron Hydrochloride for Injection in Preventing Nausea and Vomiting Caused by Multi-cycle Immunotherapy and Chemotherapy in Patients With Esophageal Cancer and Lung Cancer

NCT07596732Not ApplicableNot Yet Recruiting

Statewide Unified Network for Remote Intervention of Strength and Exercise

NCT07583316Phase 1Not Yet Recruiting

A Phase 1 First-in-Human Study of CRPA1A2, a MAGE-A1/HLA-A*02:01 Bispecific T-Cell Engager, in Patients With Solid Tumors

NCT04902872Phase 1Completed

Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors

NCT05187182Phase 1Recruiting

CA-4948 in Combination With FOLFOX/PD-1 Inhibitor +/- Trastuzumab for Untreated Unresectable Gastric and Esophageal Cancer

NCT06143748Phase 2Active Not RecruitingPrimary

Combination of Cadonilimab and Chemoradiotherapy in Esophageal Cancer (EC-CRT-006)

NCT05861947Phase 1Terminated

A Phase 1 Clinical Trial of AUR106 in Patients With Relapsed Advanced Malignancies

NCT03482791Not ApplicableActive Not RecruitingPrimary

Proton Beam Therapy in the Treatment of Esophageal Cancer

NCT02530983Recruiting

Mayo Clinic Upper Digestive Disease Survey

NCT05706558Recruiting

Retrospective Review of Esophageal Cancer at MSKCC

NCT07070466Phase 2Recruiting

Ivonescimab in Comb. With FOLFOX in Advanced HER2 Neg. GEA

NCT04075305Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

NCT07440212Not Yet RecruitingPrimary

Clinical Study on Noninvasive Evaluation of Ivonescimab Antibody Distribution and Expression in Esophageal Cancer Patients by 89Zr-AK112 PET Imaging

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