Key Insights

Highlights

Success Rate

68% trial completion

Published Results

20 trials with published results (17%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

11.6%

14 terminated out of 121 trials

Success Rate

68.2%

-18.3% vs benchmark

Late-Stage Pipeline

5%

6 trials in Phase 3/4

Results Transparency

67%

20 of 30 completed with results

Key Signals

20 with results68% success14 terminated

Data Visualizations

Phase Distribution

101Total
Not Applicable (24)
Early P 1 (1)
P 1 (26)
P 2 (44)
P 3 (5)
P 4 (1)

Trial Status

Recruiting42
Completed30
Terminated14
Unknown11
Active Not Recruiting11
Not Yet Recruiting8

Trial Success Rate

68.2%

Benchmark: 86.5%

Based on 30 completed trials

Clinical Trials (121)

Showing 20 of 20 trials
NCT07392892Phase 2Recruiting

Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer

NCT07284186Phase 1Recruiting

First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors

NCT07059611Phase 2Not Yet Recruiting

Neoadjuvant Intra-tumoral RP2 and FLOT in Gastroesophageal Adenocarcinoma

NCT06071845Not ApplicableRecruiting

Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples

NCT01196390Phase 3CompletedPrimary

Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer

NCT07544589Phase 1Recruiting

A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

NCT07603375Phase 2Not Yet RecruitingPrimary

Upfront Chemotherapy With Radiation Therapy (CRT) Followed by Chemotherapy in Localized Esophageal Adenocarcinoma

NCT03604991Phase 2Suspended

Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

NCT06324357Phase 1Recruiting

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

NCT05152147Phase 3Active Not Recruiting

A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers

NCT07546812Phase 2Recruiting

Study of Denikitug (GS-1811) Given Alone or With Nivolumab or Chemotherapy in Adults With Metastatic Gastric, Gastroesophageal Junction (GEJ), and Esophageal Adenocarcinomas

NCT07432295Phase 2Recruiting

Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)

NCT06732388Phase 2Not Yet Recruiting

Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's Esophagus

NCT04939051Phase 2Recruiting

Obeticholic Acid for Prevention in Barrett's Esophagus

NCT04389632Phase 1Recruiting

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

NCT07212491Enrolling By Invitation

Minimally Invasive Molecular Approaches for the Detection of Barrett's Esophagus- High Grade Dysplasia and Esophageal Adenocarcinoma

NCT07021066Phase 1Recruiting

Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of BL-M05D1 in Subjects With Solid Tumors

NCT02521285Phase 2Active Not Recruiting

Aspirin in Preventing Disease Recurrence in Patients With Barrett Esophagus After Successful Elimination by Radiofrequency Ablation

NCT04114136Phase 2Recruiting

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

NCT06340711Phase 2RecruitingPrimary

Study of Suratadenoturev (OBP-301) in Combination With Pembrolizumab in Esophagogastric Adenocarcinoma

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