Key Insights

Highlights

Success Rate

90% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 30/100

Termination Rate

3.7%

2 terminated out of 54 trials

Success Rate

90.5%

+3.9% vs benchmark

Late-Stage Pipeline

63%

34 trials in Phase 3/4

Results Transparency

0%

0 of 19 completed with results

Key Signals

90% success

Data Visualizations

Phase Distribution

54Total
Not Applicable (13)
Early P 1 (3)
P 2 (4)
P 3 (1)
P 4 (33)

Trial Status

Completed19
Recruiting14
Not Yet Recruiting12
Unknown5
Terminated2
Active Not Recruiting1

Trial Success Rate

90.5%

Benchmark: 86.6%

Based on 19 completed trials

Clinical Trials (54)

Showing 20 of 20 trials
NCT04843982Phase 4TerminatedPrimary

Immunoinflammatory Regulation of Esketamine in Septic Patients

NCT06051227Phase 3Terminated

Fentanyl OR Esketamine for Traumatic PAIN (FORE-PAIN) Trial

NCT06566482Phase 4Completed

Mini-dose Dexmedetomidine-Esketamine Supplemented Analgesia in Patients at High-risk of OSA

NCT07753772Phase 4Not Yet Recruiting

Dexmedetomidine-Esketamine Combination on Depression and Anxiety After Laparoscopic Ureteral Reconstruction

NCT07748884Phase 4Not Yet Recruiting

Comparing Esketamine and Remazolam With Propofol for Breathing Safety in Pediatric Gastroscopy

NCT05950646Phase 4Completed

Mini-dose Dexmedetomidine-Esketamine Infusion and Perioperative Sleep Quality

NCT07151716Phase 4Completed

Sedation With Dexmedetomidine-esketamine Combination and Delirium in ICU Patients

NCT07639099Phase 4Not Yet Recruiting

Intranasal Esketamine-dexmedetomidine Combination and Postpartum Depression

NCT07610343Phase 4Not Yet Recruiting

Intranasal Dexmedetomidine-esketamine on Sleep and Cognition in Older Adults With Mild-to-moderate Cognitive Impairment

NCT07576517Phase 4Not Yet Recruiting

Dexmedetomidine-esketamine and tDCS for Prevention of Neurocognitive Complications After Surgery

NCT07576543Phase 4Not Yet Recruiting

Long-term Follow-up of Dexmedetomidine-esketamine and tDCS for Neurocognitive Complications After Surgery

NCT07230171Not ApplicableRecruiting

The Efficacy and Safety of Short Term S-ketamine Infusion as an Adjunctive Therapy in Patients With Fibromyalgia

NCT07525999Phase 4Not Yet Recruiting

Dexmedetomidine-esketamine Combination and Chronic Postsurgical Pain After Spinal Surgery

NCT07523321Phase 4Not Yet Recruiting

Dexmedetomidine-esketamine Combination and Moderate-to-severe Pain After Spinal Surgery

NCT07523334Phase 4Not Yet Recruiting

Impact of Esketamine on Delayed Neurocognitive Recovery in Older Patients

NCT06062550Phase 4Active Not Recruiting

Different Dose Esketamine and Dexmedetomidine Combination for Supplemental Analgesia After Scoliosis Correction Surgery

NCT07308756Phase 4Recruiting

Impact of Perioperative Dexmedetomidine and Esketamine on Postoperative Quality of Recovery

NCT07145775Phase 4Completed

Dexmedetomidine-esketamine-ropivacaine Versus Sufentanil-ropivacaine for Epidural Labor Analgesia

NCT07479602Phase 4Recruiting

Intranasal Dexmedetomidine-esketamine Administration and Postoperative Pain in Pediatric Patients

NCT07247968Early Phase 1RecruitingPrimary

Subanesthetic Esketamine in Modified ECT for Severe Depression in Adolescents: Clinical and Mechanistic Study

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