Key Insights

Highlights

Success Rate

100% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 17/100

Termination Rate

0.0%

0 terminated out of 18 trials

Success Rate

100.0%

+13.5% vs benchmark

Late-Stage Pipeline

28%

5 trials in Phase 3/4

Results Transparency

60%

9 of 15 completed with results

Key Signals

9 with results100% success

Data Visualizations

Phase Distribution

15Total
Not Applicable (4)
P 1 (1)
P 2 (5)
P 3 (5)

Trial Status

Completed15
Unknown2
Enrolling By Invitation1

Trial Success Rate

100.0%

Benchmark: 86.5%

Based on 15 completed trials

Clinical Trials (18)

Showing 18 of 18 trials
NCT06388642Phase 1CompletedPrimary

Pharmacokinetics of Afamelanotide in Erythropoietic Protoporphyria Patients

NCT05020184Phase 2CompletedPrimary

Effect of Oral Cimetidine in the Protoporphyrias

NCT05308472Phase 2CompletedPrimary

Study of Bitopertin to Evaluate the Safety, Tolerability, Efficacy, and PPIX Concentrations in Participants With EPP

NCT05883748Phase 2Enrolling By InvitationPrimary

HELIOS: Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability, and Efficacy of DISC-1459 (Bitopertin) in Participants With EPP or XLP

NCT05780840Not ApplicableUnknownPrimary

Protection Against Visible Light by Dihydroxyacetone in Erythropoietic Protoporphyria

NCT05572125CompletedPrimary

Iron Therapy in Erythropoietic Protoporphyria

NCT00979745Phase 3CompletedPrimary

Phase III Confirmatory Study in Erythropoietic Protoporphyria (EPP)

NCT04578496Phase 3CompletedPrimary

A Safety Extension Study in Patients With Erythropoietic Protoporphyria (EPP)

NCT02979249Not ApplicableCompletedPrimary

Oral Iron for Erythropoietic Protoporphyrias

NCT01688895CompletedPrimary

Erythropoietic Protoporphyrias: Studies of the Natural History, Genotype-Phenotype Correlations, and Psychosocial Impact

NCT01097044Phase 2CompletedPrimary

Phase II Confirmatory Study in Erythropoietic Protoporphyria (EPP)

NCT04053270Phase 3CompletedPrimary

Multicentre Phase III Erythropoietic Protoporphyria Study

NCT01605136Phase 3CompletedPrimary

Phase III Confirmatory Study in Erythropoietic Protoporphyria

NCT03682731CompletedPrimary

Light Exposure Patterns and Symptoms Among Patients With Erythropoietic Protoporphyria

NCT01422915Phase 2CompletedPrimary

Sorbent Therapy of the Cutaneous Porphyrias

NCT00004831Not ApplicableCompletedPrimary

Study of Cysteine Hydrochloride for Erythropoietic Protoporphyria

NCT00004940Phase 3CompletedPrimary

Phase III Study of L-Cysteine in Patients With Erythropoietic Protoporphyria

NCT00206869Not ApplicableUnknownPrimary

Does Exercise and Heat Increase the Lightsensibility in Patients With Erythropoietic Protoporphyria

Showing all 18 trials

Research Network

Activity Timeline