Key Insights

Highlights

Success Rate

86% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

5.9%

1 terminated out of 17 trials

Success Rate

85.7%

-0.8% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

67%

4 of 6 completed with results

Key Signals

4 with results86% success

Data Visualizations

Phase Distribution

14Total
P 1 (3)
P 2 (11)

Trial Status

Completed6
Unknown5
Recruiting4
Terminated1
Withdrawn1

Trial Success Rate

85.7%

Benchmark: 86.5%

Based on 6 completed trials

Clinical Trials (17)

Showing 17 of 17 trials
NCT07027345Phase 2RecruitingPrimary

A Phase II, Placebo Controlled, Clinical Trial of Topical TolaSure Targeting Aggregated Mutant Keratin in Epidermolysis Bullosa Simplex

NCT06136403Phase 2RecruitingPrimary

A 44-week Monocentric Open Study Assessing the Efficacy and Safety of Deucravacitinib in Adults With Inflammatory Genodermatoses

NCT04213703Withdrawn

A Pilot Study to Explore the Role of Gut Flora in Epidermolysis Bullosa

NCT06509984Phase 2RecruitingPrimary

A 20-Week Study Assessing the Efficacy of Apremilast in Patients with EB Simplex Generalized

NCT03269474Recruiting

Computational Drug Repurposing for All EBS Cases

NCT05062070Phase 1CompletedPrimary

Safety and Efficacy of Topical TolaSure Targeting Aggregated Mutant Keratin in Severe Epidermolysis Bullosa Simplex

NCT03453632Phase 2UnknownPrimary

Injections of Botulinic Toxin in Plantar Lesions of Localized Epidermolysis Bullosa Simplex

NCT04908215Phase 2CompletedPrimary

INM-755 (Cannabinol) Cream for Treatment of Epidermolysis Bullosa

NCT02960997Phase 2CompletedPrimary

Using Topical Sirolimus 2% for Patients With Epidermolysis Bullous Simplex (EBS) Study

NCT05033574Unknown

The State of Sexual Development in Children With Inherited Epidermolysis Bullosa

NCT03389308Phase 2Completed

Long Term Open-label Study Evaluating Safety of Diacerein 1% Ointment Topical Formulation in Subjects With Epidermolysis Bullosa Simplex

NCT03472287Phase 1Completed

To Evaluate the Pharmacokinetic of Diacerein and Rhein After Maximum Use in Patients With Epidermolysis Bullosa (EB)

NCT03154333Phase 2TerminatedPrimary

Safety and Efficacy of Diacerein 1% Ointment for Subjects With Epidermolysis Bullosa Simplex (EBS)

NCT02592954Phase 1CompletedPrimary

Effect of Broccoli Sprout Extract on Keratinocyte Differentiation in Normal Skin

NCT03016715Phase 2UnknownPrimary

Using Topical Sirolimus 2% for Patients With Epidermolysis Bullous Simplex (EBS) Study

NCT02470689Phase 2UnknownPrimary

Diacerin for the Treatment of Epidermolysis Bullosa Simplex

NCT00936533Phase 2UnknownPrimary

Botulinumtoxin A Treatment in Epidermolysis Bullosa Simplex and Pachyonychia Congenita

Showing all 17 trials

Research Network

Activity Timeline