Key Insights

Highlights

Success Rate

80% trial completion

Published Results

16 trials with published results (31%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 39/100

Termination Rate

13.7%

7 terminated out of 51 trials

Success Rate

80.0%

-6.5% vs benchmark

Late-Stage Pipeline

25%

13 trials in Phase 3/4

Results Transparency

57%

16 of 28 completed with results

Key Signals

16 with results80% success

Data Visualizations

Phase Distribution

41Total
Not Applicable (6)
Early P 1 (3)
P 1 (7)
P 2 (12)
P 3 (11)
P 4 (2)

Trial Status

Completed28
Terminated7
Recruiting4
Withdrawn4
Unknown3
Active Not Recruiting3

Trial Success Rate

80.0%

Benchmark: 86.5%

Based on 28 completed trials

Clinical Trials (51)

Showing 20 of 20 trials
NCT06834035Phase 1RecruitingPrimary

Targeting Collagen VII Antibodies With IV IgG in Dystrophic Epidermolysis Bullosa

NCT04853667CompletedPrimary

Improve Adherence to Weak or Strong Opioid Analgesics at the Time of Care in Children With Hereditary Epidermolysis Bullosa

NCT07050810Early Phase 1Enrolling By InvitationPrimary

Thera-Clean® Microbubbles System in Patients With Skin Diseases

NCT06917690Phase 3RecruitingPrimary

A Study to Learn About the Safety and Efficacy of the Drug Oleogel-S10 in Japanese Patients With Epidermolysis Bullosa

NCT05464381Phase 3Active Not RecruitingPrimary

Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Epidermolysis Bullosa (Phase III, Cross-over)

NCT05838092Phase 3Active Not RecruitingPrimary

Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Epidermolysis Bullosa (Phase III)

NCT03730584Not ApplicableCompletedPrimary

Evaluation of the Efficacy of ROPIVACAINE in Children and Young Adults With Hereditary Epidermolysis Bullosa

NCT05725018Phase 3Active Not RecruitingPrimary

A Phase 3b Study for the Treatment of Dystrophic Epidermolysis Bullosa (DEB) in New and Previously EB-101 Treated Patients

NCT04213703WithdrawnPrimary

A Pilot Study to Explore the Role of Gut Flora in Epidermolysis Bullosa

NCT06330350Recruiting

Qualitative Study in Patients With Genodermatoses and Healthcare Professionals on Reproductive Counselling

NCT06330324Enrolling By Invitation

Reproductive Options in Inherited Skin Diseases

NCT05533866Early Phase 1CompletedPrimary

Characterization of the Microbiome in Colonized Dystrophic and Junctional Epidermolysis Bullosa Wounds Before and After Use of APR-TD011 ® Spray Solution

NCT03928093Phase 3Completed

Pregabalin Treatment for RDEB Pain and Itch

NCT02582775Phase 2CompletedPrimary

MT2015-20: Biochemical Correction of Severe EB by Allo HSCT and Serial Donor MSCs

NCT02670837Not ApplicableCompletedPrimary

Study of Cellutome System for Treatment of Individual Lesions in EB Pts

NCT01033552Phase 1CompletedPrimary

Biochemical Correction of Severe EB by Allo HSCT and "Off-the-shelf" MSCs

NCT05378997Phase 1Completed

Safety, Tolerability, and Pharmacokinetics of Ascending Topical Doses of TCP-25 Applied to Epidermal Suction Blister Wounds, Non-Healing Leg Ulcers and Patients With Dystrophic Epidermolysis Bullosa.

NCT03269474RecruitingPrimary

Computational Drug Repurposing for All EBS Cases

NCT03942250Not ApplicableCompletedPrimary

Uses of Irradiated Human Amniotic Membrane in the Treatment of Dystrophic Epidermolysis Bullosa Patients

NCT01263379Phase 1Completed

Gene Transfer for Recessive Dystrophic Epidermolysis Bullosa

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