Key Insights

Highlights

Success Rate

75% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

8.3%

5 terminated out of 60 trials

Success Rate

75.0%

-11.5% vs benchmark

Late-Stage Pipeline

5%

3 trials in Phase 3/4

Results Transparency

20%

3 of 15 completed with results

Key Signals

3 with results75% success

Data Visualizations

Phase Distribution

54Total
Not Applicable (11)
Early P 1 (1)
P 1 (12)
P 2 (27)
P 3 (3)

Trial Status

Recruiting15
Completed15
Unknown13
Not Yet Recruiting6
Active Not Recruiting6
Terminated5

Trial Success Rate

75.0%

Benchmark: 86.5%

Based on 15 completed trials

Clinical Trials (60)

Showing 20 of 20 trials
NCT06300424Phase 2Active Not Recruiting

Neoadjuvant Almonertinib Followed by Chemo-immunotherapy in II-IIIB EGFR-mutant NSCLC

NCT07548060Phase 2Recruiting

A Phase II Study of Sacituzumab Tirumotecan in Combination With Furmonertinib in Patients With Non-squamous Non-Small Cell Lung Cancer Who Have Progressed After EGFR-TKI and Platinum-Based Chemotherapy

NCT03909334Phase 2Active Not Recruiting

Study of Osimertinib With and Without Ramucirumab in Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

NCT06238882Not ApplicableRecruiting

Nitroglycerin Plus Radiotherapy Versus Conventional Radiotherapy in Patients With Lung Cancer.

NCT06186401Phase 1RecruitingPrimary

Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells

NCT07461727Phase 1Not Yet Recruiting

An Open-Label, Single-Arm, Dose-Escalation Phase I Study Evaluating the Safety, Tolerability, and Preliminary Efficacy of EDB-102 in Patients With EGFR L858R-Mutant, Third-Generation TKI-Resistant Advanced Non-Small Cell Lung Cancer With Liver Metastases

NCT04013542Phase 1Active Not Recruiting

Ipilimumab and Nivolumab in Combination With Radiation Therapy in Treating Patients With Stage 2-3 Non-small Lung Cancer

NCT03042221Recruiting

Early Rebiopsy to Identify Biomarkers of Tumor Cell Survival Following EGFR, ALK, ROS1 or BRAF TKI Therapy

NCT03065387Phase 1Active Not Recruiting

Neratinib and Everolimus, Palbociclib, or Trametinib in Treating Participants With Refractory and Advanced or Metastatic Solid Tumors With EGFR Mutation/Amplification, HER2 Mutation/Amplification, or HER3/4 Mutation or KRAS Mutation

NCT06716580Not ApplicableRecruiting

EQUAL: EGFR ctDNA QUantative Assessment for Lung Cancer Screening in Asian and Latinx Populations

NCT05370469Not ApplicableActive Not Recruiting

Real-Time Monitoring of Symptoms in Lung Cancer Patients Receiving Oral Targeted Therapies

NCT03049618Phase 2Completed

Recombinant EphB4-HSA Fusion Protein and Pembrolizumab, MK-3475

NCT04695925Phase 3Active Not Recruiting

Osimertinib Monotherapy or Combination With Chemotherapy for Advanced NSCLC Concurrent EGFR and TP53 Mutations

NCT03653546Phase 2Completed

First Line Treatment in EGFR Mutation Positive Advanced NSCLC Patients With Central Nervous System (CNS) Metastases

NCT05517083Not ApplicableCompleted

Feasibility of Intratumoral Washing Fluid for Detecting EGFR Mutations in Lung Cancer

NCT04206072Phase 2Completed

D-0316 Versus Icotinib in Patients With Locally Advanced or Metastatic EGFR Sensitising Mutation Positive NSCLC

NCT03175224Phase 2Recruiting

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

NCT04042558Phase 2Completed

A Study Evaluating Platinum-Pemetrexed-Atezolizumab (+/-Bevacizumab) for Patients With Stage IIIB/IV Non-squamous Non-small Cell Lung Cancer With EGFR Mutations, ALK Rearrangement or ROS1 Fusion Progressing After Targeted Therapies

NCT03755102Early Phase 1CompletedPrimary

A Pilot Study of Dacomitinib With or Without Osimertinib for Patients With Metastatic EGFR Mutant Lung Cancers With Disease Progression on Osimertinib.

NCT04512430Phase 2Terminated

Neo-DIANA: Neoadjuvant Treatment for EGFR Mutated Patients

Scroll to load more

Research Network

Activity Timeline