Key Insights

Highlights

Success Rate

67% trial completion

Treatment Research

8 treatments under study, led by Control

Research Leaders

6 sponsors active, led by The Mediterranean Institute for Transplantation and Advanced Specialized Therapies

Related Conditions

Often studied with 13 related conditions

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

14.3%

1 terminated out of 7 trials

Success Rate

66.7%

-19.9% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

150%

3 of 2 completed with results

Key Signals

3 with results67% success

Data Visualizations

Phase Distribution

5Total
Not Applicable (4)
Phase 2 (1)

Trial Status

Completed2
Not Yet Recruiting2
Unknown1
Terminated1
Recruiting1

Trial Success Rate

66.7%

Benchmark: 86.6%

Based on 2 completed trials

Clinical Trials (7)

Showing 7 of 7 trials
NCT07692490Not ApplicableRecruiting

Avoiding Recooling After Normothermic Machine Perfusion in Liver Transplantation

NCT07658794Not Yet Recruiting

Intraoperative Assessment of Microcirculatory Function Using Vascular Occlusion Test During Liver Transplantation

NCT07674394Not ApplicableNot Yet Recruiting

New Biomarkers for Organ Viability Assessment During Hypothermic Machine Perfusion in Liver Transplantation: the Role of Extemporaneous Histological Examination.

NCT03031470Phase 2Terminated

Pilot Study of Reparixin for Early Allograft Dysfunction Prevention in Liver Transplantation

NCT04203004Not ApplicableUnknown

HOPE With Cytokine Filtration in Liver Transplantation (Cyto-HOPE)

NCT02798861Completed

Controlled Attenuation Parameter (CAP) in Liver Allografts

NCT01887171Not ApplicableCompletedPrimary

Evaluation of Preimplantation Portal Vein and Hepatic Artery Flushing With Tacrolimus

Showing all 7 trials

Research Network

Common Treatments

  • Control1
  • Hope With Cytokine Filtration By Cytosorb1
  • Hypothermic Oxygenated Machine Perfusion Hopedhope1
  • No Recooling Before Liver Implantation1
  • Reparixin1

Active Sponsors

  • The Mediterranean Institute for Transplantation and Advanced Specialized Therapies2
  • Dompé Farmaceutici S.p.A1
  • Andres Duarte-Rojo1
  • Ippokrateio General Hospital of Thessaloniki1
  • Papa Giovanni XXIII Hospital1

Top Investigators

Related Conditions

  • Liver Transplantation Lt2
  • Ischemiareperfusion Injury2
  • Primary Nonfunction2
  • Liver Transplantation2
  • Liver Steatosis1

Activity Timeline