Key Insights

Highlights

Success Rate

90% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 27/100

Termination Rate

4.0%

1 terminated out of 25 trials

Success Rate

90.0%

+3.5% vs benchmark

Late-Stage Pipeline

16%

4 trials in Phase 3/4

Results Transparency

44%

4 of 9 completed with results

Key Signals

4 with results90% success

Data Visualizations

Phase Distribution

19Total
Not Applicable (1)
P 1 (9)
P 2 (5)
P 3 (4)

Trial Status

Completed9
Recruiting7
Withdrawn4
Active Not Recruiting2
Not Yet Recruiting1
Terminated1

Trial Success Rate

90.0%

Benchmark: 86.5%

Based on 9 completed trials

Clinical Trials (25)

Showing 20 of 20 trials
NCT07011589Phase 1Not Yet Recruiting

Targeting Collagen VII Antibodies in Bullous Diseases Using Efgartigimod IV (VYVGART)

NCT06834035Phase 1Recruiting

Targeting Collagen VII Antibodies With IV IgG in Dystrophic Epidermolysis Bullosa

NCT06892639Phase 3Active Not RecruitingPrimary

Evaluation of D-Fi for the Treatment of Wounds Due to DEB

NCT07016750Phase 3RecruitingPrimary

A Study Comparing KB803 and Matched Placebo in Patients With Dystrophic Epidermolysis Bullosa

NCT06594393Phase 2Recruiting

A Phase 2 Study of TCP-25 Gel in Patients With Epidermolysis Bullosa, STEP-study

NCT06713434Phase 1Active Not Recruiting

Pilot Study of ELK-003 Eye Drops for Treating Ocular Manifestations of Epidermolysis Bullosa

NCT07230223Phase 1RecruitingPrimary

Effect of Ev.FV on Wound Healing in Dystrophic Epidermolysis Bullosa

NCT04173650Phase 1RecruitingPrimary

MSC EVs in Dystrophic Epidermolysis Bullosa

NCT04757727CompletedPrimary

Gynecological Follow-up of Patients With Dystrophic Epidermolysis Bullosa (EBD)

NCT05157958Phase 2RecruitingPrimary

Study to Evaluate Safety and Efficacy of ALLO-ASC-SHEET in Subjects With Dystrophic Epidermolysis Bullosa

NCT04917874Phase 3CompletedPrimary

A Long-term Treatment With B-VEC for Dystrophic Epidermolysis Bullosa

NCT03183934CompletedPrimary

A Follow-up Study to Evaluate the Efficacy and Safety of ALLO-ASC-DFU in ALLO-ASC-EB-101 Clinical Trial

NCT02579369Phase 1CompletedPrimary

Study to Evaluate the Safety of ALLO-ASC-DFU in the Subjects With Dystrophic Epidermolysis Bullosa

NCT05529134Phase 1UnknownPrimary

Study of PTW-002 in Patients With Dominant or Recessive Dystrophic Epidermolysis Bullosa Due to Mutation(s) in Exon 73 of the COL7A1 Gene

NCT04491604Phase 3CompletedPrimary

Ph 3 Efficacy and Safety of B-VEC for the Treatment of DEB

NCT03536143Phase 1CompletedPrimary

A Phase I/II Study of KB103, a Topical HSV1-COL7, on DEB Patients

NCT03578029Phase 2Terminated

Evaluation of the Safety and Efficacy Study of RGN-137 Topical Gel for Junctional and Dystrophic Epidermolysis Bullosa

NCT04214002WithdrawnPrimary

The Natural History of Wounds in Patients With Dystrophic Epidermolysis Bullosa (DEB)

NCT04917887RecruitingPrimary

Long-Term Follow-up Protocol

NCT02178969CompletedPrimary

Short Term Observational Study in DEB Patients

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