Key Insights

Highlights

Success Rate

62% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

11.1%

8 terminated out of 72 trials

Success Rate

61.9%

-24.6% vs benchmark

Late-Stage Pipeline

6%

4 trials in Phase 3/4

Results Transparency

38%

5 of 13 completed with results

Key Signals

5 with results62% success

Data Visualizations

Phase Distribution

59Total
Early P 1 (3)
P 1 (30)
P 2 (22)
P 3 (4)

Trial Status

Recruiting20
Completed13
Active Not Recruiting12
Unknown10
Terminated8
Not Yet Recruiting5

Trial Success Rate

61.9%

Benchmark: 86.5%

Based on 13 completed trials

Clinical Trials (72)

Showing 20 of 20 trials
NCT05139017Phase 2RecruitingPrimary

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

NCT04002947Phase 2Recruiting

Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell Lymphoma

NCT07709624Active Not RecruitingPrimary

Evaluating the Treatment Outcomes of Tafasitamab in Patients With Relapsed/ Refractory Diffuse Large B-cell Lymphoma: a Real-world Evidence Study

NCT03625037Phase 1Active Not RecruitingPrimary

First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma

NCT05653271Phase 1Completed

ACE1831 in Adult Subjects With Relapsed/ Refractory CD20-expressing B-cell Malignancies

NCT07643805Phase 1Not Yet RecruitingPrimary

Single-Arm Clinical Study of EZH2i in Combination With Glofitamab + GemOx in Patients With Relapsed/ Refractory DLBCL

NCT04974216Phase 2Active Not RecruitingPrimary

Study of Tafasitamab and Lenalinomide Associated to Rituximab in Frontline Diffuse Large B-Cell Lymphoma Patients of 80 y/o or Older

NCT03731234Phase 2Active Not RecruitingPrimary

Ibrutinib + R-CHOP Followed by Ibrutinib Maintenance

NCT07259070Phase 1RecruitingPrimary

Multicenter, Single-Arm Exploratory Phase I Clinical Study (Assessment of Safety and Efficacy) of Fully Human BAFF-R Chimeric Antigen Receptor T-Cell Injection in Relapsed/Refractory BAFF-R-Positive B-Cell Lymphoma

NCT06014762Phase 1Active Not Recruiting

P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies

NCT07570017Phase 1Not Yet RecruitingPrimary

A Study of Rocbrutinib Combined With R-GemOx in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma

NCT05253118Phase 2Active Not RecruitingPrimary

Relapsed or Refractory Primary Diffuse Large B-cell Lymphoma (DLBCL) of the Central Nervous System (CNS)

NCT06544265Phase 1Recruiting

SynKIR-310 for Relapsed/Refractory B-NHL

NCT04088890Phase 1Completed

Autologous CD22 CAR T Cells in Adults w/ Recurrent or Refractory B Cell Malignancies

NCT07498920Not Yet RecruitingPrimary

Gut Microbiome in DLBCL Treated With Glofitamab

NCT05546268Phase 1Active Not Recruiting

Study of Oral MRT-2359 in Selected Cancer Patients

NCT04512716Early Phase 1Recruiting

Iomab-ACT: A Pilot Study of 131-I Apamistamab Followed by CD19-Targeted CAR T-Cell Therapy for Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia or Diffuse Large B-Cell Lymphoma

NCT05544019Phase 1Recruiting

Study of SGR-1505 in Mature B-Cell Neoplasms

NCT03758989Phase 2RecruitingPrimary

A Study of PET Adapted Therapy and Non-invasive Monitoring for Previously Untreated Limited Stage Diffuse Large B Cell Lymphoma

NCT03943901Phase 2Active Not Recruiting

Split-Dose R-CHOP for Older Adults With DLBCL

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