Key Insights

Highlights

Success Rate

60% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

11.4%

8 terminated out of 70 trials

Success Rate

60.0%

-26.5% vs benchmark

Late-Stage Pipeline

6%

4 trials in Phase 3/4

Results Transparency

42%

5 of 12 completed with results

Key Signals

5 with results60% success

Data Visualizations

Phase Distribution

58Total
Early P 1 (3)
P 1 (29)
P 2 (22)
P 3 (4)

Trial Status

Recruiting21
Completed12
Active Not Recruiting10
Unknown10
Terminated8
Not Yet Recruiting5

Trial Success Rate

60.0%

Benchmark: 86.5%

Based on 12 completed trials

Clinical Trials (70)

Showing 20 of 20 trials
NCT07570017Phase 1Not Yet RecruitingPrimary

A Study of Rocbrutinib Combined With R-GemOx in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma

NCT05139017Phase 2RecruitingPrimary

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

NCT03625037Phase 1Active Not RecruitingPrimary

First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma

NCT04002947Phase 2Recruiting

Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell Lymphoma

NCT05253118Phase 2Active Not RecruitingPrimary

Relapsed or Refractory Primary Diffuse Large B-cell Lymphoma (DLBCL) of the Central Nervous System (CNS)

NCT06544265Phase 1Recruiting

SynKIR-310 for Relapsed/Refractory B-NHL

NCT04088890Phase 1Completed

Autologous CD22 CAR T Cells in Adults w/ Recurrent or Refractory B Cell Malignancies

NCT07498920Not Yet RecruitingPrimary

Gut Microbiome in DLBCL Treated With Glofitamab

NCT05546268Phase 1Active Not Recruiting

Study of Oral MRT-2359 in Selected Cancer Patients

NCT06014762Phase 1Recruiting

P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies

NCT04512716Early Phase 1Recruiting

Iomab-ACT: A Pilot Study of 131-I Apamistamab Followed by CD19-Targeted CAR T-Cell Therapy for Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia or Diffuse Large B-Cell Lymphoma

NCT05544019Phase 1Recruiting

Study of SGR-1505 in Mature B-Cell Neoplasms

NCT03758989Phase 2RecruitingPrimary

A Study of PET Adapted Therapy and Non-invasive Monitoring for Previously Untreated Limited Stage Diffuse Large B Cell Lymphoma

NCT03943901Phase 2Active Not Recruiting

Split-Dose R-CHOP for Older Adults With DLBCL

NCT04855253Phase 1SuspendedPrimary

Ph I/II Study of E7777 Prior to CAR-T for R/R LBCL

NCT07335120RecruitingPrimary

A Real-world Data and Sample Compendium of Frail and/or Multiply Treated Large B-cell Lymphoma

NCT03463057Phase 2Active Not Recruiting

The Feasibility and Clinical Efficacy of Atezolizumab Consolidation Treatment in High Risk (IPI > 2) DLBCL

NCT03731234Phase 2Active Not RecruitingPrimary

Ibrutinib + R-CHOP Followed by Ibrutinib Maintenance

NCT04594798Phase 2Active Not RecruitingPrimary

A Study of Polatuzumab Vedotin, Rituximab and Dose Attenuated CHP in Older Patients With DLBCL

NCT07162012Early Phase 1Recruiting

Safety and Efficacy of Anti-EBV Autologous TCR-T Cell Injection in Relapsed/Refractory EBV-Positive Lymphoma

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