Key Insights

Highlights

Success Rate

100% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

0.0%

0 terminated out of 29 trials

Success Rate

100.0%

+13.5% vs benchmark

Late-Stage Pipeline

10%

3 trials in Phase 3/4

Results Transparency

28%

5 of 18 completed with results

Key Signals

5 with results100% success

Data Visualizations

Phase Distribution

21Total
Not Applicable (2)
P 1 (6)
P 2 (10)
P 3 (2)
P 4 (1)

Trial Status

Completed18
Recruiting4
Unknown3
Active Not Recruiting3
Not Yet Recruiting1

Trial Success Rate

100.0%

Benchmark: 86.5%

Based on 18 completed trials

Clinical Trials (29)

Showing 20 of 20 trials
NCT07541430Phase 2RecruitingPrimary

A Study in Adults With Desmoid Tumors

NCT07170644Phase 2Active Not RecruitingPrimary

A Study of Nirogacestat in Japanese Adults With Desmoid Tumors/Aggressive Fibromatosis (DT/AF)

NCT05041036UnknownPrimary

Individual Patient Compassionate Use of Nirogacestat

NCT07461246Active Not Recruiting

Familial Adenomatous Poliposys Italian Network (Rete Italiana Poliposi Adenomatosa Familiare)

NCT07176689Phase 4RecruitingPrimary

Nirogacestat in Premenopausal Females With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)

NCT04871282Phase 2Active Not Recruiting

A Study of AL102 in Patients With Progressing Desmoid Tumors

NCT06081400Not ApplicableRecruitingPrimary

Cryoablation Versus Medical Therapy in Desmoid Tumors Progressing After Watchful Waiting

NCT05949099Phase 2RecruitingPrimary

Study of Cryoablation and Nirogacestat for Desmoid Tumor

NCT06258421CompletedPrimary

Burden of Disease and Living Situation in Desmoid Patients

NCT03190174Phase 1Completed

Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers

NCT03785964Phase 3CompletedPrimary

Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)

NCT02076906Phase 1Completed

MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors

NCT03802084Phase 1CompletedPrimary

A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumor

NCT06355921Not ApplicableNot Yet RecruitingPrimary

A Prospective Clinical Study on the Safety and Efficacy of Radiofrequency Ablation for the Treatment of Patients With Desmoid Tumors

NCT06195085Completed

CT-guided Radioactive Iodine-125 Seed Implantation for Recurrent Desmoid Tumors

NCT04289077CompletedPrimary

Quality of Life of Patients With Desmoid-type Fibromatosis

NCT01265030Phase 1CompletedPrimary

A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis

NCT03459469Phase 1CompletedPrimary

Phase I, Open-label, Non-randomized Study to Evaluate Safety of BC2059

NCT05561036Phase 3UnknownPrimary

A Randomized, Double-blind,Phase Ⅲ Study of Liposome Doxorubicin in Desmoid Tumor

NCT00068419Phase 2CompletedPrimary

Sulindac and Tamoxifen in Treating Patients With Desmoid Tumor

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