Key Insights

Highlights

Success Rate

79% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

12.8%

5 terminated out of 39 trials

Success Rate

79.2%

-7.3% vs benchmark

Late-Stage Pipeline

8%

3 trials in Phase 3/4

Results Transparency

26%

5 of 19 completed with results

Key Signals

5 with results79% success

Data Visualizations

Phase Distribution

30Total
Not Applicable (7)
P 1 (6)
P 2 (14)
P 3 (3)

Trial Status

Completed19
Unknown6
Terminated5
Recruiting4
Not Yet Recruiting2
Withdrawn2

Trial Success Rate

79.2%

Benchmark: 86.5%

Based on 19 completed trials

Clinical Trials (39)

Showing 20 of 20 trials
NCT07499128Not ApplicableNot Yet RecruitingPrimary

Continuous Temperature Monitoring (CTM) for Cytokine Release Syndrome (CRS), an Immune-Related Adverse Event

NCT05905328Phase 1RecruitingPrimary

Study of CTO1681 for the Prevention and Treatment of CRS in DLBCL Patients Receiving CAR T-Cell Therapy

NCT07390071Not ApplicableRecruiting

Multimodal Telerehabilitation in Patients Undergoing CAR-T Cell Immunotherapy

NCT04150913Phase 2Completed

A Phase 2 Trial of Anakinra for the Prevention of CAR-T Cell Mediated Neurotoxicity

NCT04975555Phase 2Active Not RecruitingPrimary

Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy

NCT07169487Phase 1RecruitingPrimary

Adjunctive Methylene Blue for Immunotherapy-related CRS and ICANS: Phase I Study

NCT06703216Phase 1Not Yet Recruiting

Pre-emptive Anakinra for Cytokine Event Reduction

NCT04979884Phase 3Completed

Safety and Effectiveness of Cyclosporin in the Management of COVID19 ARDS Patients in Alexandria University Hospital

NCT06447376Phase 1Recruiting

Study of Cytokine Release Syndrome Prophylaxis and Treatment With Siltuximab Prior to Epcoritamab

NCT06352866Phase 2Withdrawn

Siltuximab for Cytokine Release Syndrome Prophylaxis Prior to tx w/ Teclistamab in RRMM

NCT04071366Phase 2CompletedPrimary

A Study of Itacitinib for the Prevention of Cytokine Release Syndrome Induced by Immune Effector Cell Therapy

NCT03557749Terminated

Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies

NCT04540120Phase 2Terminated

Safety and Efficacy of Dapansutrile for Treatment of Moderate COVID-19 Symptoms and Evidence of Early Cytokine Release Syndrome

NCT04366908Phase 2Completed

Prevention and Treatment With Calcifediol of COVID-19 Induced Acute Respiratory Syndrome

NCT05349669Phase 2CompletedPrimary

Jafron Haemoadsorption During Cardiopulmonary Bypass

NCT04643678Phase 2Completed

Anakinra in the Management of COVID-19 Infection

NCT04415073Phase 2Terminated

A Phase 2 Study to Evaluate Axatilimab for Hospitalized Participants With Respiratory Involvement Secondary to COVID-19

NCT05414162Unknown

Multiparametric Cardiac MRI in Patients Under CAR T-cell Therapy

NCT04720378Phase 1CompletedPrimary

Safety and Tolerability Study of IV ST266 in COVID-19 Subjects

NCT04377503Phase 2TerminatedPrimary

Tocilizumab Versus Methylprednisolone in the Cytokine Release Syndrome of Patients With COVID-19

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