Key Insights

Highlights

Success Rate

63% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

14.1%

10 terminated out of 71 trials

Success Rate

63.0%

-23.5% vs benchmark

Late-Stage Pipeline

3%

2 trials in Phase 3/4

Results Transparency

53%

9 of 17 completed with results

Key Signals

9 with results63% success

Data Visualizations

Phase Distribution

58Total
Not Applicable (10)
Early P 1 (2)
P 1 (29)
P 2 (15)
P 3 (2)

Trial Status

Recruiting25
Completed17
Active Not Recruiting13
Terminated10
Unknown4
Withdrawn1

Trial Success Rate

63.0%

Benchmark: 86.5%

Based on 17 completed trials

Clinical Trials (71)

Showing 20 of 20 trials
NCT06984328Phase 2Active Not RecruitingPrimary

Study of the Effectiveness and Safety of Acasunlimab Alone and With Pembrolizumab to Treat Advanced Melanoma of the Skin That Has Returned After Treatment With an Approved Checkpoint Inhibitor Therapy (ABBIL1TY MELANOMA-07)

NCT04778449RecruitingPrimary

Quality of Life, Lifestyle, and Psychosocial Factors in Patients With Melanoma

NCT05520099Active Not Recruiting

Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform

NCT07519655Phase 1Recruiting

Phase 1 Study of PF-08046033 in Advanced Solid Tumors

NCT06624644Phase 2Recruiting

A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma

NCT05571839Phase 1Active Not RecruitingPrimary

A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors

NCT03699995Not ApplicableTerminatedPrimary

MoleMapper, Visiomed, and Confocal Microscopy in Screening Participants for Melanoma

NCT05628883Phase 1Completed

Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma

NCT05267626Phase 1Recruiting

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

NCT03620019Phase 2Completed

Denosumab + PD-1 in Subjects With Stage III/ IV Melanoma

NCT06008977Not ApplicableActive Not RecruitingPrimary

Exercise to Boost Response to Checkpoint Blockade Immunotherapy

NCT06223659Phase 2RecruitingPrimary

EMLA Topical Cream for Treatment of Pain in Patients Receiving Intra-Dermal Technetium 99 Injections for Lymphoscintigraphy for Skin Cancers

NCT04020809Phase 1Active Not RecruitingPrimary

Neoadjuvant Atezolizumab in Cutaneous Melanoma

NCT04792463Recruiting

Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome

NCT04855435Phase 1Recruiting

Safety and Preliminary Efficacy of MBS8(1V270) in Cancer Patients With Advanced Solid Tumours

NCT06305962Early Phase 1Recruiting

177Lu-anti-PD-L1 sdAb in Metastatic Solid Tumors

NCT06999980Phase 2RecruitingPrimary

Neo IRENIE (NEOadjuvant Ipilimumab, RElatlimab, NIvolumab Evaluation)

NCT03767348Phase 2Active Not Recruiting

Study of RP1 Monotherapy and RP1 in Combination With Nivolumab (IGNYTE)

NCT05358938Early Phase 1Active Not RecruitingPrimary

Exercise to Boost Response to Checkpoint Blockade Immunotherapy

NCT07376317Phase 2Active Not Recruiting

Optimization of Immunotherapy Treatment for Advanced Melanoma in the Context of the Public Brazilian Health System (OTIMAS)

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