Key Insights

Highlights

Success Rate

58% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

17.6%

13 terminated out of 74 trials

Success Rate

58.1%

-28.5% vs benchmark

Late-Stage Pipeline

3%

2 trials in Phase 3/4

Results Transparency

50%

9 of 18 completed with results

Key Signals

9 with results58% success13 terminated

Data Visualizations

Phase Distribution

60Total
Not Applicable (11)
Early P 1 (2)
P 1 (30)
P 2 (15)
P 3 (2)

Trial Status

Recruiting26
Completed18
Terminated13
Active Not Recruiting11
Unknown3
Not Yet Recruiting2

Trial Success Rate

58.1%

Benchmark: 86.6%

Based on 18 completed trials

Clinical Trials (74)

Showing 20 of 20 trials
NCT05267626Phase 1Recruiting

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

NCT07519655Phase 1Recruiting

Phase 1 Study of PF-08046033 in Advanced Solid Tumors

NCT06984328Phase 2TerminatedPrimary

Study of the Effectiveness and Safety of Acasunlimab Alone and With Pembrolizumab to Treat Advanced Melanoma of the Skin That Has Returned After Treatment With an Approved Checkpoint Inhibitor Therapy (ABBIL1TY MELANOMA-07)

NCT07680699RecruitingPrimary

NEOSENT: Early Anti-PD-1 Therapy In High-Risk Stage II Melanoma

NCT05571839Phase 1TerminatedPrimary

A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors

NCT05520099Active Not Recruiting

Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform (ELEPHAS-02)

NCT04702854Not ApplicableTerminatedPrimary

Evaluation of Ultrasound Biomicroscopy in the Local Staging of Cutaneous Melanoma

NCT06967961Not ApplicableRecruiting

Research of Double-positive Circulating Cells (Tumor Marker / CD45+) in Several Types of Metastatic Cancers

NCT04855435Phase 1Recruiting

Safety and Preliminary Efficacy of MBS8(1V270) in Cancer Patients With Advanced Solid Tumours

NCT03947385Phase 1Recruiting

Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

NCT07621614Not ApplicableNot Yet Recruiting

A Study on How to Safely Guide Surgery for Melanoma and Similar Skin Tumors in Children Using Pathology and Genetic Information

NCT06319196Phase 2RecruitingPrimary

Clear Me: Interception Trial to Detect and Clear Molecular Residual Disease in Patients With High-risk Melanoma

NCT04253080Not ApplicableCompletedPrimary

Expression of IL4 Induced Gene 1 in Patients With Cutaneous Melanoma: Value in Prognosis and/or in Predictive Response to Immune Checkpoint Inhibitors

NCT07600476Phase 1RecruitingPrimary

A First-in-Human Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of KUP-101A in Patients With Selected Advanced Solid Tumors

NCT04778449RecruitingPrimary

Quality of Life, Lifestyle, and Psychosocial Factors in Patients With Melanoma

NCT06624644Phase 2Recruiting

A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma

NCT03699995Not ApplicableTerminatedPrimary

MoleMapper, Visiomed, and Confocal Microscopy in Screening Participants for Melanoma

NCT05628883Phase 1Completed

Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma

NCT03620019Phase 2Completed

Denosumab + PD-1 in Subjects With Stage III/ IV Melanoma

NCT06008977Not ApplicableActive Not RecruitingPrimary

Exercise to Boost Response to Checkpoint Blockade Immunotherapy

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