Key Insights

Highlights

Success Rate

89% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 30/100

Termination Rate

6.1%

2 terminated out of 33 trials

Success Rate

88.9%

+2.4% vs benchmark

Late-Stage Pipeline

27%

9 trials in Phase 3/4

Results Transparency

31%

5 of 16 completed with results

Key Signals

5 with results89% success

Data Visualizations

Phase Distribution

26Total
Not Applicable (6)
Early P 1 (1)
P 1 (3)
P 2 (7)
P 3 (4)
P 4 (5)

Trial Status

Completed16
Unknown10
Recruiting4
Terminated2
Enrolling By Invitation1

Trial Success Rate

88.9%

Benchmark: 86.5%

Based on 16 completed trials

Clinical Trials (33)

Showing 20 of 20 trials
NCT00867269Recruiting

Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ Lymphocytopenia

NCT00001352Recruiting

Fungal Infection Susceptibility

NCT03945448Phase 2RecruitingPrimary

Single Dose Liposomal Amphotericin for Asymptomatic Cryptococcal Antigenemia

NCT06666322Phase 2Recruiting

Platform Trial For Cryptococcal Meningitis

NCT06414512Phase 2CompletedPrimary

Optimizing the Dose of Flucytosine for the Treatment of Cryptococcal Meningitis

NCT06178627Phase 4Enrolling By InvitationPrimary

Amphotericin B for Non-HIV Cryptococcal Meningitis Patients

NCT04031833Phase 1CompletedPrimary

Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial (EnACT)

NCT05685641Not ApplicableUnknown

Point of Care Tests to Identify Opportunistic Infections in Advanced HIV Patients in Mexico City

NCT05541107Phase 3UnknownPrimary

Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial 3

NCT05471063Not ApplicableUnknownPrimary

Clinical Study of ABCD in the Treatment of Cryptococcal Meningitis

NCT03226379Not ApplicableCompleted

Driving Reduced AIDS-associated Meningo-encephalitis Mortality

NCT04532463CompletedPrimary

Clinical Effectiveness and Safety of Amphotericin B With Flucytosine-Fluconazole Therapy for Cryptococcal Meningitis

NCT04296292Completed

The Lived Experience of Participants in an African Randomised Trial

NCT00885703Phase 1CompletedPrimary

High-Dose Fluconazole for the Treatment of Cryptococcal Meningitis in HIV-Infected Individuals

NCT04072640Early Phase 1UnknownPrimary

Three Induction Treatments on Cryptococcal Meningitis

NCT01075152Phase 4CompletedPrimary

Cryptococcal Optimal ART Timing Trial

NCT01802385Phase 3CompletedPrimary

Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis

NCT01535469Phase 4CompletedPrimary

Operational Research for Cryptococcal Antigen Screening

NCT04140461Phase 3UnknownPrimary

AmB Dose for Cryptococcal Meningitis

NCT02434172CompletedPrimary

CryptoART Study: Decreasing Mortality Associated With Initiation of Antiretroviral Therapy in Sub-Saharan Africa

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Research Network

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