Key Insights

Highlights

Success Rate

79% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.5%

3 terminated out of 24 trials

Success Rate

78.6%

-7.9% vs benchmark

Late-Stage Pipeline

4%

1 trials in Phase 3/4

Results Transparency

64%

7 of 11 completed with results

Key Signals

7 with results79% success

Data Visualizations

Phase Distribution

22Total
Not Applicable (4)
P 1 (14)
P 2 (3)
P 4 (1)

Trial Status

Completed11
Unknown5
Terminated3
Recruiting2
Withdrawn2
Not Yet Recruiting1

Trial Success Rate

78.6%

Benchmark: 86.5%

Based on 11 completed trials

Clinical Trials (24)

Showing 20 of 20 trials
NCT07329686Phase 1Recruiting

Clinical Study of Intrastromal Anti-VEGF Injection for Corneal Neovascularization.

NCT04787471Phase 2RecruitingPrimary

Corneal Crosslinking for Treatment of Corneal Neovascularization

NCT00555594Phase 2CompletedPrimary

Prospective Study to Determine the Effect of Subconjunctival Bevacizumab (AVASTIN) in Corneal Neovascularization

NCT06412718Not Yet Recruiting

Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies

NCT05659940UnknownPrimary

Correlation Between a Novel Subset of Neutrophil and Corneal Neovascularization.

NCT00559936Phase 1CompletedPrimary

Topical Avastin for Treatment of Corneal Neovascularization

NCT05011916Phase 1UnknownPrimary

The Safety and Efficacy of KDR2-2 Suspension Eye Drops in the Treatment of Corneal Neovascularization

NCT04620109Phase 1UnknownPrimary

Clinical Evaluation of Safety and Tolerability of KDR2-2 Eye Drops in Healthy Volunteers With Pharmacokinetic Assessment

NCT01996826Phase 1CompletedPrimary

A Multi-Center Study of the Safety and Efficacy of Bevacizumab in High-Risk Corneal Transplant Survival

NCT04215393Phase 1UnknownPrimary

An Exploratory Clinical Trial Evaluating the Tolerability and Efficacy of KH906 in Patients With Corneal Neovascularization

NCT02797704Phase 1TerminatedPrimary

Subconjunctival Aflibercept (EYLEA®) for the Treatment of Corneal Neovascularization

NCT01072357Phase 1CompletedPrimary

Safety and Efficacy of Bevacizumab in High-Risk Corneal Transplant Survival

NCT01257750Phase 1CompletedPrimary

Treatment of Corneal Neovascularization With Topical Pazopanib

NCT00769145Phase 1CompletedPrimary

Ranibizumab for the Inhibition of Neovascularization in the Cornea Following Corneal Transplant Surgery

NCT00915590Phase 1TerminatedPrimary

Topical IL-1-Ra for Treatment of Corneal Neovascularization

NCT02042027Phase 1WithdrawnPrimary

Subconjunctival IVIg (Gamunex-C) Injection for Corneal Neovascularization and Inflammatory Conditions

NCT01868360Phase 1TerminatedPrimary

Using Aflibercept Injection to Treat Blood Vessel Growth Over the Cornea

NCT00515684Not ApplicableWithdrawnPrimary

Corneal Thinning During Topical Bevacizumab Therapy

NCT00004430Not ApplicableCompletedPrimary

Randomized Study of Photodynamic Therapy Using Dihematoporphyrin in Patients With Corneal Neovascularization

NCT00512876Not ApplicableCompletedPrimary

Effectiveness and Safety of Topical Bevacizumab (Avastin) for Treatment of Corneal Neovascularization

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