Congenital Central Hypoventilation Syndrome
8
3
3
2
Key Insights
Highlights
Success Rate
50% trial completion
Treatment Research
5 treatments under study, led by Mdp
Research Leaders
16 sponsors active, led by Ilya Khaytin
Related Conditions
Often studied with 17 related conditions
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 87/100
25.0%
2 terminated out of 8 trials
50.0%
-36.6% vs benchmark
0%
0 trials in Phase 3/4
50%
1 of 2 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 2 completed trials
Clinical Trials (8)
International Congenital Central Hypoventilation Syndrome (CCHS) Registry and CCHS SHARE
Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS)
CCHS Secure Health-hub Advancing Research Efforts (CCHS SHARE)
Therapeutic Effect of Desogestrel on Ventilatory Control in Patients With Congenital Central Hypoventilation Syndrome
Prevalence of Rest Dyspnea and Impact of Non Invasive Ventilation on Breathing Sensations in CCHS Patients
European Home Mechanical Ventilation Registry
Evaluation of the Awakening Capability by a Vibrating Bracelet (BRASSARD)
Late-onset Congenital Central Hypoventilation Syndrome and the Mutation of Phox2B Gene
Research Network
Common Treatments
- Mdp1
- Desogestrel1
- Nih Toolbox Cognition Battery1
- Positive Airway Pressure Noninvasive Mechanic Ventilation1
- Vibrating Bracelet1
Active Sponsors
- Ilya Khaytin2
- Ann & Robert H Lurie Children's Hospital of Chicago2
- Children's Hospital Los Angeles2
- Clinical Trial Center North Hamburg Germany1
- Great Ormond Street Hospital for Children NHS Foundation Trust1
Top Investigators
Ann & Robert H Lurie Children's Hospital of Chicago
NIHR Respiratory Biomedical Research Unit, Royal Brompton and Harefield NHS Foundation Trust, United Kingdom
Groupe Hospitalier Pitie-Salpetriere
Children's Hospital Los Angeles
Great Ormond Street Hospital-London (GOSH)
Related Conditions
- Cchs2
- Obesity Hypoventilation Syndrome1
- Healthy Volunteers1
- Duchenne Muscular Dystrophy1
- Cchs With Neural Crest Tumor1