Key Insights

Highlights

Success Rate

84% trial completion

Published Results

59 trials with published results (27%)

Research Maturity

119 completed trials (54% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

10.4%

23 terminated out of 222 trials

Success Rate

83.8%

-2.8% vs benchmark

Late-Stage Pipeline

21%

47 trials in Phase 3/4

Results Transparency

50%

59 of 119 completed with results

Key Signals

59 with results84% success23 terminated

Data Visualizations

Phase Distribution

156Total
Not Applicable (34)
Early P 1 (1)
P 1 (18)
P 2 (56)
P 3 (31)
P 4 (16)

Trial Status

Completed119
Recruiting30
Terminated23
Unknown17
Active Not Recruiting15
Not Yet Recruiting11

Trial Success Rate

83.8%

Benchmark: 86.6%

Based on 119 completed trials

Clinical Trials (222)

Showing 20 of 20 trials
NCT06651281Phase 3Recruiting

Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)

NCT07851207Not Yet RecruitingPrimary

A Study to Assess Guselkumab in Participants With Moderate-to-Severe Inflammatory Bowel Disease in Real Life Italian Setting

NCT07296315Phase 2RecruitingPrimary

Confirmatory Clinical Study in Active Ulcerative Colitis

NCT07848737Not Yet RecruitingPrimary

A Real-World Study of Guselkumab Persistence and Effectiveness in Participants With Crohn's Disease or Ulcerative Colitis

NCT07012395Phase 2Recruiting

A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

NCT07652294Phase 2Enrolling By Invitation

Long-term Safety and Efficacy of Multiple Long-acting Antibodies Alone and in Combinations for IBD

NCT05528510Phase 3Active Not RecruitingPrimary

A Study of Guselkumab Therapy in Participants With Moderately to Severely Active Ulcerative Colitis

NCT03596645Phase 3Active Not RecruitingPrimary

A Study to Assess the Efficacy and Safety of Golimumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis

NCT07463183Phase 2RecruitingPrimary

A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)

NCT05242484Phase 2Active Not RecruitingPrimary

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

NCT05092269Phase 3Active Not Recruiting

A Long-term Extension Study of Ustekinumab in Pediatric Participants

NCT07302360RecruitingPrimary

A Real-World Study of Guselkumab in Chinese Participants With Ulcerative Colitis

NCT06260163Phase 3Active Not RecruitingPrimary

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis

NCT07746765Not Yet Recruiting

A Study of Continued Use of Guselkumab in Participants With Crohn's Disease and Ulcerative Colitis in Real World Setting

NCT07242248Recruiting

A Study to Observe Real-world Evidence of Guselkumab Treatment in Participants With Ulcerative Colitis and Crohn's Disease in the United Kingdom (UK)

NCT07102368Recruiting

A Study to Generate Real-world Evidence of Guselkumab Effectiveness in Inflammatory Bowel Disease in Germany

NCT06867094Phase 2Active Not RecruitingPrimary

A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Ulcerative Colitis

NCT07196748Phase 3RecruitingPrimary

A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

NCT06663332Phase 3Recruiting

A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants

NCT07606339Recruiting

A Study of Guselkumab in Participants With Crohn's Disease and Ulcerative Colitis

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