Key Insights

Highlights

Success Rate

78% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

10.5%

2 terminated out of 19 trials

Success Rate

77.8%

-8.7% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

29%

2 of 7 completed with results

Key Signals

2 with results78% success

Data Visualizations

Phase Distribution

17Total
Not Applicable (2)
P 1 (7)
P 2 (8)

Trial Status

Recruiting8
Completed7
Terminated2
Not Yet Recruiting1
Unknown1

Trial Success Rate

77.8%

Benchmark: 86.5%

Based on 7 completed trials

Clinical Trials (19)

Showing 19 of 19 trials
NCT06322342Phase 2Completed

Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent

NCT05098613Phase 1Recruiting

Preliminary Safety and Tolerability of CD19x22 CAR T Cells in Adolescent and Adult R/R B-NHL Patients

NCT05222269Phase 2TerminatedPrimary

[68Ga]Ga-PentixaFor PET Imaging in CNS Lymphoma Patients

NCT06343311Phase 1Recruiting

T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)

NCT05828628RecruitingPrimary

CLIMB: CNS Lymphoma Imaging and Molecular Biomarkers Study

NCT06730542Phase 1RecruitingPrimary

Zanubrutinib in Combination With Pola-R-CHP and High-dose Methotrexate in Patients With Secondary CNS Lymphoma

NCT06901999Phase 2Not Yet RecruitingPrimary

Methotrexate or Thiotepa Combined With R-CHOP and Orelabrutinib in CNSL Patients

NCT06876688Phase 2RecruitingPrimary

Relma-cel Followed by Tislelizumab for the Treatment of Relapsed/Refractory CNS Large B-Cell Lymphoma

NCT05351593Phase 1RecruitingPrimary

Tafasitamab Plus Lenalidomide in Relapsed CNS Lymphoma

NCT06132737Phase 1RecruitingPrimary

[90Y]Y-PTT Endoradiotherapy in CNS Lymphoma Patients

NCT04841434Phase 1CompletedPrimary

A Phase I/II Study to Investigate the Use of VORAXAZE™ As Intended Intervention in Patients with CNSL

NCT00596154Phase 2CompletedPrimary

Rituximab, Methotrexate, Procarbazine and Vincristine Followed by High-dose Chemotherapy With Autologous Stem-cell Rescue in Newly-diagnosed Primary CNS Lymphoma

NCT05926427Phase 2RecruitingPrimary

Orelabrutinib Combined With Rituximab and Chemotherapy for Relapsed/Refractory B-Cell Lymphoma Patients With Central Nervous System Involvement

NCT05242146Phase 1TerminatedPrimary

GB5121 in Adult Patients With Relapsed/Refractory CNS Lymphoma

NCT01182415Phase 2Completed

High Dose Chemotherapy and Stem Cell Transplant for Non-Hodgkin's Lymphoma or Central Nervous System (CNS) Lymphoma

NCT05117814Not ApplicableUnknownPrimary

Zanubrutinib Monotherapy in Relapsed/Refractory Central Nervous System Lymphoma

NCT05293990Not ApplicableCompleted

Usefulness of Gadovist-enhanced FLAIR Imaging

NCT01319591CompletedPrimary

Comparison of Creatinine Clearance Calculation for Estimation of GFR in Patients Receiving HD Methotrexate

NCT01083342Phase 2CompletedPrimary

High-Dose (HD) Methotrexate (MTX) Induction Chemotherapy Followed by Alternative HD MTX-based and HD Cytarabine-based Combination Consolidation Chemotherapy for Newly Diagnosed Primary CNS Lymphoma; CISL 10-01 Study

Showing all 19 trials

Research Network

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