Key Insights

Highlights

Success Rate

69% trial completion

Published Results

17 trials with published results (23%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 64/100

Termination Rate

21.3%

16 terminated out of 75 trials

Success Rate

69.2%

-17.3% vs benchmark

Late-Stage Pipeline

19%

14 trials in Phase 3/4

Results Transparency

47%

17 of 36 completed with results

Key Signals

17 with results69% success16 terminated

Data Visualizations

Phase Distribution

57Total
Not Applicable (16)
Early P 1 (1)
P 1 (8)
P 2 (18)
P 3 (7)
P 4 (7)

Trial Status

Completed36
Terminated16
Unknown14
Recruiting3
Withdrawn3
Suspended1

Trial Success Rate

69.2%

Benchmark: 86.5%

Based on 36 completed trials

Clinical Trials (75)

Showing 20 of 20 trials
NCT04171817Phase 4Completed

Animal-Assisted Visitation Program Chlorhexidine Trial

NCT06237452Phase 3RecruitingPrimary

VE303 for Prevention of Recurrent Clostridioides Difficile Infection

NCT02636517Phase 1Enrolling By InvitationPrimary

Fecal Microbiome Transplant

NCT06071312Phase 1RecruitingPrimary

FMT in Patients With Recurrent CDI and Ulcerative Colitis: Single Infusion Versus Sequential Approach

NCT05622721Active Not Recruiting

REMBRANDT: REcovery of the MicroBiome fRom Antibiotics for Dental implanTs

NCT04036058Not ApplicableCompletedPrimary

Effect of Expanding (Gloving) Barrier Precautions for Reducing Clostridium Difficile Acquisition (and Infection) in VA

NCT04100603WithdrawnPrimary

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Clostridoides Difficile Infection

NCT03848689CompletedPrimary

FQ Restriction for the Prevention of CDI

NCT02179658Phase 3CompletedPrimary

A Study to Compare Safety and Efficacy of OPT-80(Fidaxomicin) With Vancomycin in Subjects With Clostridium Difficile-associated Diarrhea (CDAD)

NCT02254967Phase 4CompletedPrimary

A Phase IIIB/IV Study to Compare the Efficacy of Vancomycin Therapy to Extended Duration of Fidaxomicin Therapy in the Clinical Cure of Clostridium Difficile Infection (CDI) in an Older Population

NCT01901276Phase 4CompletedPrimary

Effects of Gastric Acid on Colonic Microbiome

NCT06258551Recruiting

Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients

NCT02134392Phase 1UnknownPrimary

Fecal Transplant for Pediatric Patients Who Have Recurrent C-diff Infection

NCT02797288UnknownPrimary

Immune Response to C.Difficile Infection

NCT03788434Phase 2Completed

Phase 2 Study of VE303 for Prevention of Recurrent Clostridioides Difficile Infection

NCT03857464Not ApplicableCompletedPrimary

C Difficile Near-patient Diagnostics

NCT03760484Phase 2TerminatedPrimary

Fecal Microbiota Transplant (FMT) Plus Fidaxomicin for Severe or Fulminant Clostridium Difficile Infection

NCT03617172Phase 2TerminatedPrimary

PROCLAIM -- Misoprostol in the Prevention of Recurrent CDI Prevent Recurrence of Clostridium Difficile Infection With Misoprostol

NCT03937999Phase 4TerminatedPrimary

Bezlotoxumab as Secondary Prophylaxis for C. Difficile in High-risk Hospitalized Patients Exposed to Antibiotics.

NCT02801656Phase 3WithdrawnPrimary

Fecal Microbiota Transplantation for Primary Clostridium Difficile Diarrhea

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