Key Insights

Highlights

Success Rate

86% trial completion

Published Results

73 trials with published results (32%)

Research Maturity

125 completed trials (55% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

9.2%

21 terminated out of 229 trials

Success Rate

85.6%

-0.9% vs benchmark

Late-Stage Pipeline

4%

10 trials in Phase 3/4

Results Transparency

58%

73 of 125 completed with results

Key Signals

73 with results86% success21 terminated

Data Visualizations

Phase Distribution

220Total
Not Applicable (12)
Early P 1 (2)
P 1 (101)
P 2 (95)
P 3 (10)

Trial Status

Completed125
Recruiting42
Active Not Recruiting22
Terminated21
Unknown8
Withdrawn8

Trial Success Rate

85.6%

Benchmark: 86.5%

Based on 125 completed trials

Clinical Trials (229)

Showing 20 of 20 trials
NCT07468916Phase 2Not Yet Recruiting

Ropeginterferon Alfa-2b for the Treatment of Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes and Chronic Myelomonocytic Leukemia

NCT02727803Phase 2Recruiting

Personalized NK Cell Therapy in CBT

NCT04888741Phase 2Recruiting

Methods of T Cell Depletion Trial (MoTD)

NCT03670966Phase 1Recruiting

211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome

NCT04493138Phase 1Active Not RecruitingPrimary

Azacitidine and Quizartinib for the Treatment of Myelodysplastic Syndrome or Myelodysplastic/Myeloproliferative Neoplasm With FLT3 or CBL Mutations

NCT04167917Phase 1Completed

NTX-301 in MDS/AML

NCT00843882Phase 3Active Not Recruiting

Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia

NCT04256317Phase 2Recruiting

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

NCT01522976Phase 2Active Not RecruitingPrimary

Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia

NCT05428969Phase 1Active Not Recruiting

A Study to Assess Safety, Tolerability and Preliminary Efficacy of Bexmarilimab in Combination With Standard of Care in Patients With Hematological Malignancies

NCT03418038Phase 2Recruiting

Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

NCT06439199Recruiting

Biological, Prospective Study Evaluating the Dosage of Plasma Cytokines Including the FLT3 Ligand and IL6 of Patients Treated With Non-intensive Chemotherapy

NCT01384513Phase 2Completed

A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

NCT06597734Phase 2RecruitingPrimary

A Phase 2 Study Evaluating Olutasidenib in Combination With Hypomethylating Agents in Patients With IDH1-mutated Higher-risk Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Advanced Myeloproliferative Neoplasm

NCT05038592Phase 1Active Not RecruitingPrimary

Phase I/II Study of Tagraxofusp in Combination With Decitabine for Patients With Myelomonocytic/Myeloproliferative Neoplasm and High Risk Myelodysplastic Syndromes

NCT04239157Phase 2RecruitingPrimary

A Phase II, Open-Label, Study of Subcutaneous Canakinumab, an Anti-IL-1β Human Monoclonal Antibody, for Patients With Low or Int-1 Risk IPSS/IPSS-R Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia

NCT05600894Phase 2Active Not RecruitingPrimary

Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

NCT03289910Phase 2Active Not Recruiting

Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia

NCT00392353Phase 1Active Not Recruiting

Vorinostat and Azacitidine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia

NCT03722407Phase 2Active Not RecruitingPrimary

Ruxolitinib for the Treatment of Chronic Myelomonocytic Leukemia (CMML): A Phase 2 Expansion

Scroll to load more

Research Network

Activity Timeline