Key Insights

Highlights

Success Rate

73% trial completion

Published Results

23 trials with published results (23%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

15.2%

15 terminated out of 99 trials

Success Rate

73.2%

-13.3% vs benchmark

Late-Stage Pipeline

5%

5 trials in Phase 3/4

Results Transparency

56%

23 of 41 completed with results

Key Signals

23 with results73% success15 terminated

Data Visualizations

Phase Distribution

79Total
Not Applicable (6)
Early P 1 (5)
P 1 (32)
P 2 (31)
P 3 (4)
P 4 (1)

Trial Status

Completed41
Recruiting22
Terminated15
Active Not Recruiting6
Unknown5
Not Yet Recruiting5

Trial Success Rate

73.2%

Benchmark: 86.6%

Based on 41 completed trials

Clinical Trials (99)

Showing 20 of 20 trials
NCT05724121RecruitingPrimary

Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

NCT07024706Phase 2RecruitingPrimary

Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for Relapsed CLL Post-1L Finite cBTKi+BCL2i ± Obinutuzumab

NCT07741695Not Yet RecruitingPrimary

Targeting IRAK4 in Chronic Lymphocytic Leukemia

NCT07221500Phase 2RecruitingPrimary

A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)

NCT01087333Recruiting

Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment

NCT07428707Early Phase 1RecruitingPrimary

Immune Profiling of CLL/SLL Treated With First-Line Pirtobrutinib

NCT07205315Early Phase 1Recruiting

A Clinical Study Evaluating the Safety and Efficacy of GT801 Injection in Adult Patients With Relapsed/Refractory CD19-positive B-cell Hematologic Malignancies and Autoimmune Hemolytic Anemia

NCT00840853Phase 1Active Not Recruiting

Multi-virus CTLs Expressing CD19 Chimeric Receptors, CD19 Positive Malignancies Post SCT, MULTIPRAT

NCT03342144RecruitingPrimary

Study of the Use of Venetoclax in Participants With Chronic Lymphocytic Leukemia (CLL) Under Real-Life Setting

NCT06043011RecruitingPrimary

Registry Platform Hematologic Malignancies (RUBIN) - Extension of Tumor Registry Lymphatic Neoplasms

NCT04419519Phase 2Active Not RecruitingPrimary

Assessing Minimal Residual Disease by Next- Generation Sequencing to Minimize Exposure in People With CLL or SLL Who Have Been Treated With Venetoclax

NCT04447768Phase 2Active Not RecruitingPrimary

The Combination of Venetoclax and Obinutuzumab in People With Chronic Lymphocytic Leukemia (CLL)

NCT05131022Phase 1RecruitingPrimary

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

NCT07592481Not ApplicableNot Yet RecruitingPrimary

Connected Blood Pressure Monitoring in Patients With Hematologic Malignancies Initiating Covalent BTK Inhibitors

NCT07638007Recruiting

Impact of Targeted Therapy on Cancer-Related Cognitive Impairment

NCT05557695RecruitingPrimary

Observational Study of Acalabrutinib in Patients With Chronic Lymphocytic Leukaemia in the United Kingdom

NCT06528301Phase 1Recruiting

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

NCT03824483Phase 2RecruitingPrimary

Study of Zanubrutinib, Obinutuzumab, and Venetoclax in Patients With Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL)

NCT04488354Phase 1Completed

Long-term Follow-up Study for Patients Treated With CLBR001 CAR-T

NCT07030400Recruiting

Predictors of Health-Related QOL in Adults With CLL or Small Lymphocytic Lymphoma

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