Key Insights

Highlights

Success Rate

87% trial completion

Published Results

61 trials with published results (12%)

Research Maturity

213 completed trials (42% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 42/100

Termination Rate

6.5%

33 terminated out of 507 trials

Success Rate

86.6%

-0.0% vs benchmark

Late-Stage Pipeline

31%

157 trials in Phase 3/4

Results Transparency

29%

61 of 213 completed with results

Key Signals

61 with results87% success33 terminated

Data Visualizations

Phase Distribution

397Total
Not Applicable (55)
Early P 1 (4)
P 1 (91)
P 2 (90)
P 3 (47)
P 4 (110)

Trial Status

Completed213
Unknown140
Recruiting52
Terminated33
Active Not Recruiting29
Not Yet Recruiting26

Trial Success Rate

86.6%

Benchmark: 86.6%

Based on 213 completed trials

Clinical Trials (507)

Showing 20 of 20 trials
NCT07855029RecruitingPrimary

Impact of Functional Cure of Chronic Hepatitis B on Patient-Reported Outcomes (PROs)

NCT06638320Recruiting

Hepatitis Delta Virus Infection: Cross-sectional Study in Patients With Chronic Hepatitis B Virus Infection

NCT07797231Phase 3Not Yet RecruitingPrimary

Clinical Trial of TQA3605 Tablet in Combination With Nucleos(t)Ide Analogues(NAs) Versus NAs Alone for the Treatment of Patients With Chronic Hepatitis B Virus Infection Who Have Undergone Treatment and Exhibit Low Viral Load or Poor Response

NCT07852091Phase 2RecruitingPrimary

A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (A)

NCT07843446CompletedPrimary

Residual Histological Disease Across Treatment Pathways in Chronic Hepatitis B

NCT07845058Phase 2RecruitingPrimary

A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (B)

NCT05769816Phase 2RecruitingPrimary

A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (A)

NCT05841095Phase 1Active Not RecruitingPrimary

Evaluation of the Novel Therapeutic Hepatitis B Virus Synthetic Long Peptide Vaccination ISA104

NCT07589400Phase 1Not Yet Recruiting

Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Characteristics of ACT500 in Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Complicated With Chronic Hepatitis B

NCT06706310Phase 2Active Not RecruitingPrimary

Evaluate TQ-A3334 Combined Nucleoside (Acid) Analogs in the First Treatment/Treatment of Chronic HBV Infection

NCT07809165Not ApplicableNot Yet RecruitingPrimary

Sequential PD-1 Antibody and Pegylated Interferon Therapy for Nucleos(t)Ide Analogue-suppressed Chronic Hepatitis B

NCT05771402Phase 2RecruitingPrimary

A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (B)

NCT07573943Phase 4RecruitingPrimary

ASC22 Combined With Peg-IFNa in Achieving Functional Cure in Patients With Chronic Hepatitis B Virus Infection

NCT05466071RecruitingPrimary

Safety and Efficacy of TAF to Prevent MTCT of HBV in Middle/Late Pregnancies With High HBV DNA Load

NCT07777250Not Yet RecruitingPrimary

Targeting ANKRD11 Reverses HBV-Specific CD8+ T Cell Dysfunction and Tolerance

NCT06070051Phase 1CompletedPrimary

Dose-Escalation Prime/Boost Therapeutic Vaccination Study Of 2 Chimp Adenoviral Vectors in Adults With Chronic HBV On Nucleos(t)Ide Therapy

NCT07146100RecruitingPrimary

Long-term Follow-up Study to Evaluate Participants With Chronic Hepatitis B (CHB) Previously Treated With AHB-137 Injection

NCT06092333Phase 2RecruitingPrimary

VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis B

NCT07764835Not Yet Recruiting

Prospective Evaluation of Hepatocellular Carcinoma Surveillance in At-Risk Patients (Screening HCC)

NCT06993480Phase 2Active Not RecruitingPrimary

A Study to Evaluate the Antiviral Activity and Immune Response of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)

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