Key Insights

Highlights

Success Rate

86% trial completion

Published Results

61 trials with published results (12%)

Research Maturity

206 completed trials (42% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 42/100

Termination Rate

6.7%

33 terminated out of 490 trials

Success Rate

86.2%

-0.3% vs benchmark

Late-Stage Pipeline

31%

154 trials in Phase 3/4

Results Transparency

30%

61 of 206 completed with results

Key Signals

61 with results86% success33 terminated

Data Visualizations

Phase Distribution

386Total
Not Applicable (54)
Early P 1 (4)
P 1 (88)
P 2 (86)
P 3 (45)
P 4 (109)

Trial Status

Completed206
Unknown141
Recruiting42
Terminated33
Active Not Recruiting32
Not Yet Recruiting21

Trial Success Rate

86.2%

Benchmark: 86.5%

Based on 206 completed trials

Clinical Trials (490)

Showing 20 of 20 trials
NCT06993480Phase 2Active Not RecruitingPrimary

A Study to Evaluate the Antiviral Activity and Immune Response of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)

NCT07146100RecruitingPrimary

Long-term Follow-up Study to Evaluate Participants With Chronic Hepatitis B (CHB) Previously Treated With AHB-137 Injection

NCT07246889Phase 3Active Not RecruitingPrimary

Study of AHB-137 in Participants With Chronic Hepatitis B (CHB) Treated With Nucleos(t)Ide Analogues (NAs)(AUSHINE)

NCT07137910Phase 2RecruitingPrimary

A Study to Evaluate the Efficacy and Safety of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)

NCT05410496Phase 4Active Not Recruiting

Tenofovir Alafenamide Switching Therapy in Kidney or Liver Transplant Recipients With Chronic HBV Infection

NCT05343481Phase 2CompletedPrimary

Efficacy of VTP-300 in Chronic Hepatitis B Infection

NCT04980482Phase 2CompletedPrimary

Open-Label Study of AB-729, Nucleos(t)Ide Analogue and Pegylated Interferon Alfa-2a in Subjects With Chronic Hepatitis B Infection

NCT06047093Not ApplicableRecruitingPrimary

Fine Needle Aspiration (FNA) Evaluation of the Intrahepatic HBV Reservoir and Its Immunological Characteristics in Chronically HBV-infected Patients

NCT06989788Phase 1Active Not RecruitingPrimary

A Study to Evaluate the Safety and Immunogenicity of an Investigational Vaccine for Chronic Hepatitis B Virus Infection, in Healthy Adults

NCT07540637Not ApplicableNot Yet RecruitingPrimary

Assessment of Treatment Adherence and Associated Factors in Chronic HepB Patients Supported by HBVCare

NCT07537387Not Yet RecruitingPrimary

A Study on the Pursuit of Sustained Clearance of HBsAg in Chronic Hepatitis B(CHB) Patients With Previous Interferon Treatment Using Pegylated Interferon Alpha

NCT04412863Phase 2CompletedPrimary

Study of VIR-2218 With or Without Pegylated Interferon Alpha-2a for Treatment of Chronic Hepatitis B Virus Infection

NCT05960240Phase 1CompletedPrimary

Safety, Tolerability, PK & PD of AB-101 Following Oral Administration in Healthy and CHB Subjects.

NCT07520123Not ApplicableNot Yet RecruitingPrimary

Union-FAST: An Intelligent-Agent Intervention to Increase Antiviral Treatment Uptake in Diagnosed-but-Untreated Hepatitis B Patients

NCT06966908RecruitingPrimary

Hospital-Based Management of Patients With Chronic Hepatitis B Virus Infection

NCT00536627Phase 1CompletedPrimary

Efficacy and Tolerance of Naked DNA Vaccine in Patients With Chronic B Hepatitis

NCT06357806Not ApplicableActive Not RecruitingPrimary

The Treatment of PD-1 Antibody Combined With Peg-IFNα in NAs-suppressed CHB Patients

NCT06092333Phase 2RecruitingPrimary

VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis B

NCT06364930Phase 4RecruitingPrimary

SGLT2i to Prevent of Liver Complications in Patients With CHB and Diabetes Mellitus

NCT07449091Not Yet RecruitingPrimary

Adaptability of an Undetectable = Untransmissible Model for HBV

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