Key Insights

Highlights

Success Rate

60% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

16.7%

2 terminated out of 12 trials

Success Rate

60.0%

-26.6% vs benchmark

Late-Stage Pipeline

8%

1 trials in Phase 3/4

Results Transparency

67%

2 of 3 completed with results

Key Signals

2 with results60% success

Data Visualizations

Phase Distribution

6Total
P 1 (3)
P 2 (2)
P 4 (1)

Trial Status

Completed3
Recruiting3
Unknown2
Terminated2
Active Not Recruiting1
Not Yet Recruiting1

Trial Success Rate

60.0%

Benchmark: 86.6%

Based on 3 completed trials

Clinical Trials (12)

Showing 12 of 12 trials
NCT07728708Not Yet RecruitingPrimary

Effects of Axatilimab on Skin in Chronic Graft-versus-Host Disease

NCT00092235RecruitingPrimary

Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host Disease

NCT02669251Phase 1Active Not RecruitingPrimary

Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation

NCT05544032UnknownPrimary

Expanded Access of Axatilimab to Treat a Single Patient With Chronic Graft Versus Host Disease (GVHD)

NCT06824103Phase 4Recruiting

Study of Efficacy and Safety of Ruxolitinib in Chinese Participants With Corticosteroid-refractory Chronic Graft vs. Host Disease

NCT04852692TerminatedPrimary

A Study to Investigate the Comparative Effectiveness of Ibrutinib in Steroid Dependent/Refractory cGVHD Participants

NCT02759731Phase 1CompletedPrimary

Study of Baricitinib, a JAK1/2 Inhibitor, in Chronic Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation

NCT05095649Phase 2RecruitingPrimary

Donor Regulatory T-cells for cGVHD in Patients Who do Not Obtain Complete Remission With Ruxolitinib

NCT02067832UnknownPrimary

Predictive Biomarkers For Pediatric Chronic Graft-Versus-Host Disease

NCT03683498Phase 1CompletedPrimary

Donor Regulatory T-cells for Steroid-Refractory Chronic Graft-versus-host-Disease

NCT02322190Phase 2TerminatedPrimary

Biomarkers in Acute Graft-Versus-Host Disease and Extracorporeal Photopheresis Added to Investigator Chosen Therapies of Steroid Refractory Acute GVHD

NCT01221766Completed

Impact of Adnexal Involvement of the Severity and Prognosis of Chronic Graft-versus-Host Disease

Showing all 12 trials

Research Network

Activity Timeline