Key Insights

Highlights

Success Rate

60% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

18.2%

2 terminated out of 11 trials

Success Rate

60.0%

-26.5% vs benchmark

Late-Stage Pipeline

9%

1 trials in Phase 3/4

Results Transparency

67%

2 of 3 completed with results

Key Signals

2 with results60% success

Data Visualizations

Phase Distribution

6Total
P 1 (3)
P 2 (2)
P 4 (1)

Trial Status

Recruiting3
Completed3
Terminated2
Unknown2
Active Not Recruiting1

Trial Success Rate

60.0%

Benchmark: 86.5%

Based on 3 completed trials

Clinical Trials (11)

Showing 11 of 11 trials
NCT00092235RecruitingPrimary

Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host Disease

NCT02669251Phase 1Active Not RecruitingPrimary

Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation

NCT06824103Phase 4Recruiting

Study of Efficacy and Safety of Ruxolitinib in Chinese Participants With Corticosteroid-refractory Chronic Graft vs. Host Disease

NCT05544032UnknownPrimary

Expanded Access of Axatilimab to Treat a Single Patient With Chronic Graft Versus Host Disease (GVHD)

NCT04852692TerminatedPrimary

A Study to Investigate the Comparative Effectiveness of Ibrutinib in Steroid Dependent/Refractory cGVHD Participants

NCT02759731Phase 1CompletedPrimary

Study of Baricitinib, a JAK1/2 Inhibitor, in Chronic Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation

NCT05095649Phase 2RecruitingPrimary

Donor Regulatory T-cells for cGVHD in Patients Who do Not Obtain Complete Remission With Ruxolitinib

NCT02067832UnknownPrimary

Predictive Biomarkers For Pediatric Chronic Graft-Versus-Host Disease

NCT03683498Phase 1CompletedPrimary

Donor Regulatory T-cells for Steroid-Refractory Chronic Graft-versus-host-Disease

NCT02322190Phase 2TerminatedPrimary

Biomarkers in Acute Graft-Versus-Host Disease and Extracorporeal Photopheresis Added to Investigator Chosen Therapies of Steroid Refractory Acute GVHD

NCT01221766Completed

Impact of Adnexal Involvement of the Severity and Prognosis of Chronic Graft-versus-Host Disease

Showing all 11 trials

Research Network

Activity Timeline