Chronic Graft Versus Host Disease
51
13
19
16
Key Insights
Highlights
Success Rate
67% trial completion
Published Results
14 trials with published results (27%)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 47/100
15.7%
8 terminated out of 51 trials
66.7%
-19.9% vs benchmark
10%
5 trials in Phase 3/4
88%
14 of 16 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 16 completed trials
Clinical Trials (51)
Axatilimab for Sclerotic Chronic Graft-versus-Host Disease
Dental Cleaning to Prevent Chronic Graft-Versus-Host Disease
A Long-term Extension Study of PCI-32765 (Ibrutinib)
Mindfulness Intervention to Reduce Patient Reported Symptoms in Patients With Chronic Graft-Versus-Host Disease
Study to Compare the Plasma Concentration of Belumosudil Given as an Oral Suspension and as a Tablet to Healthy Adult Male Participants
Tissue Immune Landscape of Graft Versus Host Disease After Allogeneic Stem Cell Transplantation (TIL-GVHD)
Predicting the Quality of Response to Specific Treatments in Patients With cGVHD, PQRST Study
Leflunomide in Treating Patients With Steroid Dependent Chronic Graft Versus Host Disease
A Rollover Study to Provide Continued Treatment for Participants Previously Enrolled in Studies of Itacitinib
Axatilimab in Combination With Extracorporeal Photopheresis (ECP) in Chronic Graft-versus-Host Disease
BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP)
A Study of Belumosudil in Children With Chronic Graft Versus Host Disease (schoolROCK)
Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host Disease
Abatacept to Treat Steroid Refractory Chronic Graft Versus Host Disease (cGVHD)
A Clinical Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Belumosudil in Chinese Adolescents With cGVHD Who Have Had an Inadequate Response to Glucocorticoids or Other Systemic Therapies
Ibrutinib for the Prevention of Chronic Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant
A Study to Investigate Safety of Belumosudil in Participants Aged 12 Years and Above, With Chronic Graft-versus-host Disease (cGVHD)
Belumosudil and Rituximab for Primary Treatment of Chronic Graft-Versus-Host-Disease
Improving Outcomes Assessment in Chronic GVHD
Upfront Ruxolitinib for Chronic Graft-vs-host Disease