Key Insights

Highlights

Success Rate

82% trial completion

Published Results

18 trials with published results (28%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

10.8%

7 terminated out of 65 trials

Success Rate

82.1%

-4.5% vs benchmark

Late-Stage Pipeline

17%

11 trials in Phase 3/4

Results Transparency

56%

18 of 32 completed with results

Key Signals

18 with results82% success

Data Visualizations

Phase Distribution

43Total
Not Applicable (12)
P 1 (8)
P 2 (12)
P 3 (8)
P 4 (3)

Trial Status

Completed32
Unknown19
Terminated7
Active Not Recruiting3
Not Yet Recruiting2
Withdrawn1

Trial Success Rate

82.1%

Benchmark: 86.5%

Based on 32 completed trials

Clinical Trials (65)

Showing 20 of 20 trials
NCT04167358Phase 3Active Not RecruitingPrimary

Linerixibat Long-term Safety, and Tolerability Study

NCT05582447Active Not RecruitingPrimary

Osmotic Fragility in Red Blood Cells of Pediatric Patients With Cholestatic Liver Disease

NCT07247604Not Yet RecruitingPrimary

Congenital Heart Diseases and Developmental Assessment in Cholestatic Infants Under Two Years

NCT02412566UnknownPrimary

SMOF Lipid for Children With Parenteral Nutrition Induced Liver Injury

NCT04510090Phase 1Completed

Evaluate the Safety, Tolerability, and PK of EP547 in Healthy Subjects and Subjects With Cholestatic or Uremic Pruritus

NCT06610695Enrolling By InvitationPrimary

PET/CT Scans Using the Tracer 11C-Csar, a Bile Acid Analog, to Depict and Visualize Cholestatic Disorders in Patients with Genetic Liver Disorders and Healthy Individuals

NCT06604923Active Not Recruiting

PET/CT Scans Using the Tracer 11C-Csar, a Bile Acid Analog, to Depict and Visualize Changes in the Hepatobiliary System in Patients With Primary Biliary Cholangitis Before and After Treatment.

NCT02922751Completed

FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE)

NCT04604652Phase 2Completed

Open-Label Study of HTD1801 in Adult Subjects With Primary Biliary Cholangitis

NCT06364969Not Yet RecruitingPrimary

Investigation of the Pruritogens of Liver-related Diseases

NCT00826020Phase 2Completed

Evaluation of Omegaven™ Parenteral Nutrition in Patients With Total Parenteral Nutrition (TPN)-Induced Cholestasis

NCT00007020Phase 3Completed

Compassionate Treatment of Patients With Inborn Errors of Bile Acid Metabolism With Cholic Acid

NCT06005701Unknown

Mallampati Score for Prediction and Prognosis of Postoperative Mortality and Morbidity and Safety Profiles of Patients Undergoing Laparoscopic Cholecystectomy in Qassim Region

NCT05718349UnknownPrimary

FGF19 in Obstructive Cholestasis: "Unveil the Signal"

NCT04309773Phase 3Unknown

Efficacy of 24 Month of Bezafibrate in Primary Sclerosing Cholangitis With Persistent Cholestasis Despite Ursodeoxycholic Acid Therapy

NCT02936596Not ApplicableUnknown

Remission Induction of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap Syndrome

NCT00738101Not ApplicableCompletedPrimary

Compassionate Use of an Intravenous Fish Oil Emulsion in the Treatment of Liver Injury in Infants

NCT02966834Phase 2CompletedPrimary

Dose Response Study of GSK2330672 for the Treatment of Pruritus in Participants With Primary Biliary Cholangitis

NCT02148146UnknownPrimary

Use of Omega 3 Oil Emulsion for Parenteral Nutrition Associated Cholestasis

NCT02357576Phase 3CompletedPrimary

Standard Lipid Therapy vs IVFE Minimization for Prevention of PNALD

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