Key Insights

Highlights

Success Rate

96% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 30/100

Termination Rate

3.2%

2 terminated out of 63 trials

Success Rate

95.9%

+9.4% vs benchmark

Late-Stage Pipeline

33%

21 trials in Phase 3/4

Results Transparency

19%

9 of 47 completed with results

Key Signals

9 with results96% success

Data Visualizations

Phase Distribution

55Total
Not Applicable (14)
P 1 (5)
P 2 (15)
P 3 (15)
P 4 (6)

Trial Status

Completed47
Unknown8
Recruiting5
Terminated2
Active Not Recruiting1

Trial Success Rate

95.9%

Benchmark: 86.5%

Based on 47 completed trials

Clinical Trials (63)

Showing 20 of 20 trials
NCT06498817Not ApplicableRecruiting

Testing a Scalable Model of the Cholera Hospital-Based Intervention for 7 Days (CHoBI7)

NCT05814042Phase 2Completed

Next Generation ORS: Comparing ORS With Calcium vs Standard ORS in Reducing Severity of Acute Watery Diarrhea

NCT06455852Not ApplicableRecruitingPrimary

Vaccine- and Infection-derived Correlates of Protection for Cholera

NCT06193408Phase 2CompletedPrimary

Assessment of a Novel Fixed-dose Combination (FDC) Drug VR-AD-1005 for the Treatment of Acute Watery Diarrhea in Cholera

NCT03251495Phase 2CompletedPrimary

Immunologic Responses to a Live Attenuated Oral Cholera Vaccine

NCT05166850Not ApplicableRecruitingPrimary

Preventative Intervention for Cholera for 7 Days

NCT06003816Not ApplicableRecruitingPrimary

Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) Water, Sanitation, and Hygiene (WASH) Case Area Targeted Intervention (CATI)

NCT06929312Not ApplicableCompletedPrimary

Simulation Based Training In Medical Students

NCT04326478Phase 2Active Not RecruitingPrimary

Single Dose Azithromycin to Prevent Cholera in Children

NCT06104345Phase 4Completed

Immune Response Elicited by Concomitant Administration of Oral Typhoid Fever (Vivotif®) and Cholera (Dukoral®) Vaccines

NCT05829772CompletedPrimary

Impact Study of Cholera Vaccination in Endemic Areas - Seroprevalence

NCT04853186RecruitingPrimary

Impact Study of Cholera Vaccination in Endemic Areas - Clinical Surveillance

NCT04816552Not ApplicableCompletedPrimary

Water, Sanitation, and Hygiene Mobile Health Messages as an Innovative Tool to Facilitate Behavior Change

NCT02499172Not ApplicableTerminated

Follow-up of Pregnant Women After a Mass Vaccination of Oral Cholera Vaccine (ShancholTM) in Nsanje Malawi

NCT05771779Phase 3Unknown

Co-administration Study of OCV, TCV and MR

NCT01895855Phase 3CompletedPrimary

Safety and Efficacy Challenge Study of Live Oral Cholera Vaccine Candidate,PXVX0200, to Prevent Cholera

NCT02094586Phase 3CompletedPrimary

A Phase 3 Lot to Lot Consistency Study of Live Oral Cholera Vaccine, PXVX0200 in Healthy Adults

NCT02100631Phase 3CompletedPrimary

A Study of Live Oral Cholera Vaccine, PXVX200 in Healthy Older Adults

NCT01585181Phase 1CompletedPrimary

Safety and Immunogenicity of the Live Oral Cholera Vaccine Candidate PXVX0200

NCT04760236Phase 3CompletedPrimary

Immune Non-Inferiority, Safety and Lot-to-Lot Consistency of Oral Cholera Vaccine-Simplified Compared to Shanchol™

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Research Network

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