Cardiac Allograft Vasculopathy
37
4
5
14
Key Insights
Highlights
Success Rate
88% trial completion (above average)
Clinical Risk Assessment
Based on trial outcomes
Low Risk
Score: 17/100
5.4%
2 terminated out of 37 trials
87.5%
+1.0% vs benchmark
30%
11 trials in Phase 3/4
43%
6 of 14 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 14 completed trials
Clinical Trials (37)
AERIAL Trial: Antiplatelet Therapy in Heart Transplantation
MARINER Trial: Multiparametric Cardiac PET for CAV Surveillance After Heart Transplantation
Early Post Transplant Cardiac Allograft Vasculopathy
Determining the Association of Microvascular Disease as Assessed by PET and Graft Injury by Donor Derived Cell Free DNA
Comparing PCCT With ICA and IVUS in Detecting Cardiac Allograft Vasculopathy
Unraveling Mechanism of Action of Extracorporeal Photopheresis in Heart and Lung Transplant Patients
Physiologic Assessment of Microvascular Function in Heart Transplant Patients
Extracorporeal Photopheresis and Early Cardiac Graft Vasculopathy
Microvascular Cardiac Allograft Vasculopathy Trial
Impact of SGLT2 Inhibitors in Heart Transplant Recipients
Endothelin-1 and Cardiac Allograft Vasculopathy (CAV)
Cholesterol Lowering With EVOLocumab to Prevent Cardiac Allograft Vasculopathy in De-novo Heart Transplant Recipients
Tacrolimus/Everolimus vs. Tacrolimus/MMF in Pediatric Heart Transplant Recipients Using the MATE Score
Efficacy and Safety Of Alirocumab to Prevent Early Cardiac Allograft Vasculopathy in Recent Heart Transplant Recipients
Safety and Efficacy of Everolimus - Eluting Bioresorbable Vascular Scaffold for Cardiac Allograft Vasculopathy
Potential Role of Donor-derived Cell-Free DNA as a Biomarker in Cardiac Allograft Vasculopathy
The De-novo Use of Eculizumab in Presensitized Patients Receiving Cardiac Transplantation
A P2X7R Single Nucleotide Mutation Promotes Chronic Allograft Vasculopathy
Prevention of Cardiac Allograft Vasculopathy Using Rituximab (Rituxan) Therapy in Cardiac Transplantation
Cardiac Mitochondrial Function After Heart Transplantation