Key Insights

Highlights

Success Rate

71% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

19.4%

6 terminated out of 31 trials

Success Rate

71.4%

-15.1% vs benchmark

Late-Stage Pipeline

13%

4 trials in Phase 3/4

Results Transparency

60%

9 of 15 completed with results

Key Signals

9 with results71% success

Data Visualizations

Phase Distribution

29Total
P 1 (10)
P 2 (15)
P 3 (4)

Trial Status

Completed15
Terminated6
Unknown5
Recruiting2
Withdrawn1
Active Not Recruiting1

Trial Success Rate

71.4%

Benchmark: 86.5%

Based on 15 completed trials

Clinical Trials (31)

Showing 20 of 20 trials
NCT07218380Phase 3RecruitingPrimary

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

NCT03288545Phase 1TerminatedPrimary

A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer

NCT05014139Phase 1Terminated

A Study of Intravesical Enfortumab Vedotin For Treatment of Patients With Non-muscle Invasive Bladder Cancer (NMIBC)

NCT07189793Phase 2Not Yet Recruiting

Toripalimab ± Sequential Intravesical Gemcitabine-Mitomycin C for BCG-Unresponsive/-Intolerant High-Risk NMIBC: Open-Label Randomized Phase 2 Study

NCT05874921Recruiting

uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

NCT04660929Phase 1Active Not Recruiting

CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors

NCT03219333Phase 2CompletedPrimary

A Study of Enfortumab Vedotin for Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer

NCT02443324Phase 1Completed

A Study of Ramucirumab Plus Pembrolizumab in Participants With Gastric or GEJ Adenocarcinoma, NSCLC, Transitional Cell Carcinoma of the Urothelium, or Biliary Tract Cancer

NCT02451423Phase 2CompletedPrimary

Neoadjuvant Atezolizumab in Localized Bladder Cancer

NCT04039867Phase 2TerminatedPrimary

Evaluation of Oxaliplatin and Gemcitabine in Patients With Metastatic Bladder Cancer

NCT02450331Phase 3TerminatedPrimary

A Study of Atezolizumab Versus Observation as Adjuvant Therapy in Participants With High-Risk Muscle-Invasive Urothelial Carcinoma (UC) After Surgical Resection

NCT03410693Phase 2CompletedPrimary

Study of Rogaratinib (BAY1163877) vs Chemotherapy in Patients With FGFR (Fibroblast Growth Factor Receptor)-Positive Locally Advanced or Metastatic Urothelial Carcinoma

NCT05318339Phase 2UnknownPrimary

A Study of Trastuzumab and Pyrotinib in HER2 Positive Locally Advanced or Metastatic Urothelial Carcinoma

NCT03051373Phase 2CompletedPrimary

Phase 2 Trial of Nab-paclitaxel Plus S-1 vs Gemcitabine Plus Cisplatin as 1-line Chemotherapy of Patients With Local Advanced and/or Metastatic Transitional Cell Carcinoma of Urothelial Tract

NCT02793128Phase 3CompletedPrimary

The OLYMPUS Study - Optimized DeLivery of Mitomycin for Primary UTUC Study

NCT00722553Phase 2CompletedPrimary

Study of Pralatrexate to Treat Advanced or Metastatic Relapsed Transitional Cell Carcinoma of the Urinary Bladder

NCT01478685Phase 1Completed

A Phase 1 Study of CC-486 as a Single Agent and in Combination With Carboplatin or ABI-007 in Subjects With Relapsed or Refractory Solid Tumors

NCT02300610Phase 1Completed

Enzalutamide in Combination With Gemcitabine and Cisplatin in Bladder Cancer

NCT01856101Phase 2TerminatedPrimary

Study of BEZ235 as Monotherapy in Patients With Transitional Cell Carcinoma After Failure of Platinum Based Chemotherapy

NCT01529411Phase 2CompletedPrimary

Clinical Trial With Vinflunine as Maintenance Therapy in Metastatic Urothelial Cancer

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