Key Insights

Highlights

Success Rate

68% trial completion

Published Results

12 trials with published results (27%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 74/100

Termination Rate

26.7%

12 terminated out of 45 trials

Success Rate

67.6%

-18.9% vs benchmark

Late-Stage Pipeline

7%

3 trials in Phase 3/4

Results Transparency

48%

12 of 25 completed with results

Key Signals

12 with results68% success12 terminated

Data Visualizations

Phase Distribution

42Total
Not Applicable (3)
P 1 (19)
P 2 (17)
P 3 (3)

Trial Status

Completed25
Terminated12
Unknown6
Recruiting1
Active Not Recruiting1

Trial Success Rate

67.6%

Benchmark: 86.5%

Based on 25 completed trials

Clinical Trials (45)

Showing 20 of 20 trials
NCT02296684Phase 2Completed

Immunotherapy With MK-3475 in Surgically Resectable Head and Neck Squamous Cell Carcinoma

NCT03485209Phase 2Active Not Recruiting

Efficacy and Safety Study of Tisotumab Vedotin for Patients With Solid Tumors

NCT07090499Phase 1Recruiting

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

NCT05551117Phase 2Terminated

A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors

NCT02289209Phase 2Completed

Reirradiation With Pembrolizumab in Locoregional Inoperable Recurrence or Second Primary Squamous Cell CA of the Head and Neck

NCT03509012Phase 1CompletedPrimary

Immunotherapy in Combination With Chemoradiation in Patients With Advanced Solid Tumors

NCT03715946Phase 2CompletedPrimary

Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer

NCT02113878Phase 1CompletedPrimary

Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck

NCT03788785Not ApplicableCompletedPrimary

Smoking Tobacco Cessation Integrated Program of Patients Treated for the Head and the Neck Cancer

NCT01588431Phase 2CompletedPrimary

Bevacizumab/Ph 2 for Locally Advanced Head and Neck Cancer

NCT03540563Not ApplicableCompletedPrimary

ctDNA as a Biomarker for Treatment Response in HNSCC

NCT00957086Phase 3UnknownPrimary

Study of Post-Op Adjuvant Concurrent Chemo-RT With or Without Nimotuzumab for Head & Neck Cancer

NCT02101034Phase 1CompletedPrimary

PD 0332991 and Cetuximab in Patients With Incurable SCCHN

NCT03088059Phase 2UnknownPrimary

Biomarker-based Study in R/M SCCHN

NCT05845632Unknown

Time to Treatment and Disease-free Survival of Patients With High-risk Head-neck Cutaneous Squamous Cell Carcinoma

NCT03620123Phase 2Completed

A Randomized Phase II Study on the Optimization of Immunotherapy in Squamous Carcinoma of the Head and Neck

NCT02383966Phase 3CompletedPrimary

Phase III Trial to Assess Efficacy and Safety of Cetuximab for the Treatment of Chinese Participants With Head and Neck Cancer

NCT03799744Phase 1Unknown

Safety,Tolerability,and Efficacy of VCN-01 With Durvalumab in R/M Head and Neck Squamous Cell Carcinoma

NCT03735290Phase 1TerminatedPrimary

A Study to Evaluate the Safety and Effectiveness of ILIxadencel Administered Into Tumors in Combination With Checkpoint Inhibitor (CPI) in Patients With ADvanced Cancer

NCT01606566Phase 2Terminated

A Study to Evaluate the Safety and Efficacy of Amphinex Induced PCI of Bleomycin for Recurrent Head and Neck Cancer.

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