Key Insights

Highlights

Success Rate

63% trial completion

Published Results

20 trials with published results (20%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 64/100

Termination Rate

23.0%

23 terminated out of 100 trials

Success Rate

62.9%

-23.6% vs benchmark

Late-Stage Pipeline

17%

17 trials in Phase 3/4

Results Transparency

51%

20 of 39 completed with results

Key Signals

20 with results63% success23 terminated

Data Visualizations

Phase Distribution

84Total
Not Applicable (10)
P 1 (20)
P 2 (37)
P 3 (14)
P 4 (3)

Trial Status

Completed39
Terminated23
Unknown16
Recruiting13
Withdrawn4
Active Not Recruiting4

Trial Success Rate

62.9%

Benchmark: 86.5%

Based on 39 completed trials

Clinical Trials (100)

Showing 20 of 20 trials
NCT06094829CompletedPrimary

Tobacco and Alcohol Influence on Oncogenic Drivers and Somatic Evolution in the Oral Mucosa

NCT02743832Not ApplicableRecruitingPrimary

A Study on Tumor Budding Guiding Individualized Surgical Planning of Early-stage Oral Squamous Cell Carcinoma.

NCT02664935Phase 2Completed

National Lung Matrix Trial: Multi-drug Phase II Trial in Non-Small Cell Lung Cancer

NCT04564989Recruiting

Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC

NCT04892173Phase 3RecruitingPrimary

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

NCT06669572Phase 2RecruitingPrimary

Lenvatinib and Pembrolizumab to Treat Patients With Anal or Rectum Cancer That Has Gotten Worse After Initial Treatment

NCT06295809Phase 2CompletedPrimary

A Study of (Neo)Adjuvant Intismeran Autogene (V940) and Pembrolizumab in Cutaneous Squamous Cell Carcinoma (V940-007)

NCT03833167Phase 3CompletedPrimary

Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)

NCT03174275Phase 2Active Not RecruitingPrimary

Carboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and Neck Squamous Cell Carcinoma

NCT04099290Recruiting

Circulating Tumor DNA (ctDNA) in Locally Advanced Head and Neck Squamous Cell Carcinoma

NCT07339176Phase 1Not Yet Recruiting

Intratumoral N17350 in Advanced Solid Tumors

NCT04124198Not ApplicableActive Not Recruiting

Quality of Life After Primary TORS vs IMRT for Patients With Early-stage Oropharyngeal Squamous Cell Carcinoma

NCT06912087Phase 1Recruiting

Dose Finding Study of Zanzalintinib With Pembrolizumab and Cetuximab in Head and Neck SCC

NCT02442375Phase 3Completed

Uniform FDG-PET Guided Gradient Dose Prescription to Reduce Late Radiation Toxicity

NCT02549638TerminatedPrimary

Identification of Prognostic Biomarkers for Progression of Invasive Squamous Cell Carcinoma

NCT02994069Phase 2Active Not RecruitingPrimary

Cisplatin + Radiation in SCCHN and Correlation With Oxidative Stress Markers

NCT04429542Phase 1Recruiting

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

NCT03336606Phase 1Active Not Recruiting

Study of MEDI0562 Prior to Surgical Resection in Head and Neck Squamous Cell Carcinoma (HNSCC) or Melanoma

NCT03370406Phase 1RecruitingPrimary

Intralesional 5-Fluorouracil (5FU), Topical Calcipotriene Treatment for SCC

NCT00448240Phase 2Terminated

Erlotinib (Tarceva) During First Line Standard Platinum Containing Chemo for Advanced Squamous Cell Head and Neck Cancer

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