Key Insights

Highlights

Success Rate

82% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

11.1%

2 terminated out of 18 trials

Success Rate

81.8%

-4.7% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

44%

4 of 9 completed with results

Key Signals

4 with results82% success

Data Visualizations

Phase Distribution

14Total
P 1 (5)
P 2 (9)

Trial Status

Completed9
Recruiting4
Terminated2
Withdrawn1
Active Not Recruiting1
Not Yet Recruiting1

Trial Success Rate

81.8%

Benchmark: 86.5%

Based on 9 completed trials

Clinical Trials (18)

Showing 18 of 18 trials
NCT06406465Phase 2RecruitingPrimary

A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

NCT05461430Completed

Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)

NCT06041516Phase 1Recruiting

A First-in-Human Phase I Trial With Antibody Drug Conjugate ADCT-701 in Neuroendocrine Tumors, Carcinomas and Malignant Peripheral Nerve Sheath Tumors

NCT07337447Phase 2Not Yet RecruitingPrimary

Trial of FOLFIRI + Zimberelimab + Domvanalimab vs FOLFIRI With a Hybrid Synthetic Control Arm in Second Line Treatment of Neuroendocrine Carcinoma of Gastro-enteropancreatic or Unknown Origin (REWENEC 01)

NCT05237934Recruiting

Tissue Procurement and Natural History Study of Neuroendocrine Neoplasms (NENs) Including Adrenocortical Carcinoma (ACC)

NCT01876771Phase 2RecruitingPrimary

A Trial to Assess the Safety and Effectiveness of Lutetium-177 Octreotate Therapy in Neuroendocrine Tumours

NCT03037385Phase 1Completed

Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors

NCT02487095Phase 1Completed

Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers

NCT04985357Withdrawn

Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to Drugs

NCT02754297Phase 2Active Not Recruiting

Personalized PRRT of Neuroendocrine Tumors

NCT03012620Phase 2Completed

Secured Access to Pembrolizumab for Patients With Selected Rare Cancer Types

NCT04488263Terminated

Natural History Study of Children and Adults With Neuroendocrine Neoplasms (NEN)s

NCT02205515Phase 1CompletedPrimary

An Open Label, Single-Centre, Pilot Study of Everolimus With EBRT for the Treatment of mNET Liver Metastasis

NCT00511862Phase 2Completed

TheraSphere for the Treatment of Liver Metastases

NCT02315625Phase 2Terminated

Study of Mutation-Targeted Therapy With Sunitinib or Everolimus in People With Advanced Low- or Intermediate-Grade Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas With or Without Cytoreductive Surgery

NCT02250885Phase 2CompletedPrimary

KPT-330 to Treat Poorly Differentiated Lung and Gastroenteropancreatic Tumors

NCT00926640Phase 1CompletedPrimary

A Phase I Study of Belinostat in Combination With Cisplatin and Etoposide in Adults With Small Cell Lung Carcinoma and Other Advanced Cancers

NCT00353015Phase 2Completed

Irinotecan and Cisplatin for High Grade Neuroendocrine Carcinoma of the Gastrointestinal Tract

Showing all 18 trials

Research Network

Activity Timeline