Key Insights

Highlights

Success Rate

76% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

15.4%

4 terminated out of 26 trials

Success Rate

76.5%

-10.0% vs benchmark

Late-Stage Pipeline

23%

6 trials in Phase 3/4

Results Transparency

77%

10 of 13 completed with results

Key Signals

10 with results76% success

Data Visualizations

Phase Distribution

21Total
Not Applicable (2)
Early P 1 (1)
P 1 (2)
P 2 (10)
P 3 (5)
P 4 (1)

Trial Status

Completed13
Terminated4
Withdrawn3
Recruiting2
Active Not Recruiting2
Unknown1

Trial Success Rate

76.5%

Benchmark: 86.5%

Based on 13 completed trials

Clinical Trials (26)

Showing 20 of 20 trials
NCT07087054Phase 3RecruitingPrimary

Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen

NCT05361668Phase 2CompletedPrimary

Study to Evaluate the Safety, PK, and Dose Response of Paltusotine in Subjects With Carcinoid Syndrome

NCT07450287Not Yet Recruiting

CardioNETPOL National Registry of Carcinoid Heart Disease

NCT04993261Early Phase 1Active Not RecruitingPrimary

An Investigational Scan (Dual Energy CT) in Detecting Gastrointestinal Carcinoid Tumors

NCT05756608Recruiting

Fibrosis in Chronic and Delayed Myocardial Infarction

NCT05064514Not ApplicableActive Not Recruiting

Investigation of a Transcatheter Tricuspid Valved Stent Graft in Patients With Carcinoid Heart Disease

NCT03453489Phase 2CompletedPrimary

AMT-PET in Monitoring Telotristat Etiprate Treatment in Participants With MetastaticNeuroendocrine Neoplasm

NCT03223428CompletedPrimary

Real-world Evidence Study EvaLuating PAtient-Reported Outcomes With XERMELO

NCT04713202Phase 2Withdrawn

Prospective Assessment of Patients With Neuroendocrine Tumors and Current or Prior History of Carcinoid Syndrome or Diarrhea Undergoing Peptide Receptor Radionuclide Therapy With or Without Telotristat Ethyl

NCT03722511Phase 2Completed

Evaluating an Amino Acid Based Medical Food w/ Diarrhea in Carcinoid Syndrome & Other NETs

NCT00774930Phase 3CompletedPrimary

An Efficacy and Safety Study of Somatuline Depot (Lanreotide) Injection to Treat Carcinoid Syndrome

NCT04776876Phase 2Withdrawn

Retifanlimab (INCMGA00012) and Telotristat Ethyl for the Treatment of Advanced Neuroendocrine Tumors and Carcinoid Syndrome

NCT04073017Not ApplicableTerminated

Enterade in Carcinoid/Non-Carcinoid Syndrome Neuroendocrine Tumor Patients With Quality of Life Limiting Bowel Frequency

NCT01018953Phase 2TerminatedPrimary

Study to Assess the Efficacy and Safety of Different Doses of BIM 23A760 in Patients With Carcinoid Syndrome

NCT01234168Completed

A Study to Assess Neuroendocrine Tumour (NET) Patients Currently Treated by Somatuline Autogel for History of Carcinoid Syndrome Associated With Episodes of Diarrhea

NCT04039516Phase 2Unknown

Carcinoid Heart Disease and Peptide Receptor Radiotargetted Therapy

NCT04140409Phase 4Terminated

Sandostatin (Octreotide LAR) May Lead to Clinical Improvement Through Receptor Occupation Optimisation

NCT02026063Phase 3CompletedPrimary

Telotristat Etiprate - Expanded Treatment for Patients With Carcinoid Syndrome Symptoms

NCT01104415Phase 2CompletedPrimary

Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome

NCT00853047Phase 2CompletedPrimary

Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome Not Managed by Stable-Dose Octreotide Therapy

Scroll to load more

Research Network

Activity Timeline