Key Insights

Highlights

Success Rate

50% trial completion

Published Results

13 trials with published results (46%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 75/100

Termination Rate

39.3%

11 terminated out of 28 trials

Success Rate

50.0%

-36.5% vs benchmark

Late-Stage Pipeline

4%

1 trials in Phase 3/4

Results Transparency

118%

13 of 11 completed with results

Key Signals

13 with results50% success11 terminated

Data Visualizations

Phase Distribution

27Total
Not Applicable (3)
Early P 1 (1)
P 1 (13)
P 2 (9)
P 3 (1)

Trial Status

Completed11
Terminated11
Recruiting3
Active Not Recruiting1
Unknown1
Withdrawn1

Trial Success Rate

50.0%

Benchmark: 86.5%

Based on 11 completed trials

Clinical Trials (28)

Showing 20 of 20 trials
NCT04331041Phase 2Active Not Recruiting

Stereotactic Body Radiotherapy and Focal Adhesion Kinase Inhibitor in Advanced Pancreas Adenocarcinoma

NCT05111353Phase 1Completed

Neoantigen Vaccines in Pancreatic Cancer in the Window Prior to Surgery

NCT06648434Phase 1Recruiting

MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma

NCT07126158Phase 2Recruiting

Stereotactic Body Radiotherapy Plus FAK and RAF/MEK Inhibition in Advanced Pancreatic Adenocarcinoma

NCT03323944Phase 1Terminated

CAR T Cell Immunotherapy for Pancreatic Cancer

NCT05975593Not ApplicableRecruiting

MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial

NCT05252390Phase 1Terminated

NUV-868 as Monotherapy and in Combination With Olaparib or Enzalutamide in Adult Patients With Advanced Solid Tumors

NCT02905578Phase 2Completed

A Phase 2 Trial of High-dose Ascorbate for Pancreatic Cancer (PACMAN 2.1)

NCT06947395CompletedPrimary

Clinical Validation of a Blood Biomarker Test to Detect Early-Stage Pancreatic Cancer (VERIFI)

NCT04536077Phase 2Terminated

Immunologic Effects of CDX-301 and CDX-1140 in Resectable Pancreatic Cancer Patients

NCT03956056Phase 1Terminated

Neoantigen Peptide Vaccine Strategy in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy

NCT01231347Phase 3Completed

QUILT-2.014: Gemcitabine and AMG 479 in Metastatic Adenocarcinoma of the Pancreas

NCT03122106Phase 1Terminated

Neoantigen DNA Vaccine in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy

NCT04542291Phase 1Completed

Targeting Pancreatic Cancer With Sodium Glucose Transporter 2 (SGLT2) Inhibition

NCT02830620Not ApplicableCompletedPrimary

Study at the Man of the Profile of Chimiokines in the Anorexia Bound to the Cancerous Cachexy

NCT03883919Phase 1Completed

Liposomal Irinotecan Plus 5-FU / LV Combined With Paricalcitol in Patients With Advanced Pancreatic Cancer Progressed on Gemcitabine-based Therapy

NCT04123574Early Phase 1Withdrawn

A Pilot Study of BXCL701 in Patients With Pancreatic Cancer

NCT02608229Phase 1Terminated

BVD-523 Plus Nab-paclitaxel and Gemcitabine in Patients With Metastatic Pancreatic Cancer

NCT02311361Phase 1Completed

Immune Checkpoint Inhibition (Tremelimumab and/or MEDI4736) in Combination With Radiation Therapy in Patients With Unresectable Pancreatic Cancer

NCT01838317Phase 2CompletedPrimary

A Phase II Study of Pioglitazone for Patients With Cancer of the Pancreas

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