Key Insights

Highlights

Success Rate

86% trial completion

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 27/100

Termination Rate

5.3%

1 terminated out of 19 trials

Success Rate

85.7%

-0.8% vs benchmark

Late-Stage Pipeline

16%

3 trials in Phase 3/4

Results Transparency

83%

5 of 6 completed with results

Key Signals

5 with results86% success

Data Visualizations

Phase Distribution

13Total
Not Applicable (1)
P 1 (2)
P 2 (7)
P 3 (3)

Trial Status

Completed6
Recruiting6
Not Yet Recruiting4
Unknown1
Terminated1
Active Not Recruiting1

Trial Success Rate

85.7%

Benchmark: 86.5%

Based on 6 completed trials

Clinical Trials (19)

Showing 19 of 19 trials
NCT07416162Not Yet Recruiting

A Study of Iptacopan in Korean Patients With Paroxysmal Nocturnal Hemoglobinuria or C3 Glomerulopathy

NCT05083364Phase 1CompletedPrimary

Study of ARO-C3 in Adult Healthy Volunteers and Patients With Complement Mediated Renal Disease

NCT04572854Phase 2Completed

Study Assessing the Safety and Efficacy of Pegcetacoplan in Post-Transplant Recurrence of C3G or IC-MPGN

NCT03955445Phase 3RecruitingPrimary

Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN

NCT07156149RecruitingPrimary

Fabhalta Capsules Specified Drug-use Survey

NCT05647811Phase 1Not Yet RecruitingPrimary

Study of NM8074 in Adult C3 Glomerulopathy Patients

NCT05809531Phase 3Active Not Recruiting

An Open-Label, Nonrandomized, Multicenter Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan in Participants With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis

NCT05067127Phase 3Completed

Phase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis

NCT07331259Not Yet RecruitingPrimary

CHART-C3G/CLNP023B12011

NCT04729062Unknown

C3G/Primary IC-MPGN EAP

NCT06209736Phase 2RecruitingPrimary

Safety and Efficacy Study of OMS906 in Patients With C3G and ICGN

NCT04183101Phase 2RecruitingPrimary

Evaluation of a Renin Inhibitor, Aliskiren, Compared to Enalapril, in C3 Glomerulopathy

NCT07029542RecruitingPrimary

Home Reported Outcomes in C3G Study

NCT06786338Phase 2Not Yet Recruiting

A Study of SGB-9768 in Patients with Complement-mediated Kidney Diseases

NCT06065852Recruiting

National Registry of Rare Kidney Diseases

NCT03459443Phase 2Terminated

A Proof of Concept Study for a 12 Month Treatment in Patients With C3G or IC-MPGN Treated With ACH-0144471

NCT03369236Phase 2CompletedPrimary

A Proof-of-Concept Study of Danicopan for 6 Months of Treatment in Participants With C3 Glomerulopathy (C3G)

NCT03723512Not ApplicableCompleted

Non-contrast Enhanced MRI in Patients With C3 Glomerulopathy (C3G) or Immune-complex Membranoproliferative Glomerulonephritis (IC-MPGN) Enrolled in the ACH471-205 Study

NCT03124368Phase 2Completed

A Proof-of-Mechanism Study to Determine the Effect of Danicopan on C3 Levels in Participants With C3G or IC-MPGN

Showing all 19 trials

Research Network

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