BRCA Mutation
29
9
15
2
Key Insights
Highlights
Success Rate
100% trial completion (above average)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 37/100
0.0%
0 terminated out of 29 trials
100.0%
+13.5% vs benchmark
3%
1 trials in Phase 3/4
50%
1 of 2 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 2 completed trials
Clinical Trials (29)
Prediction of Germline BRCA 1/2 Genes From Healthy Ovaries
The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics
A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
Olaparib and ASTX727 in BRCA1/2- and Homologous Recombination Deficient (HRD)-Mutated Tumors
The GENPET Study - An Imaging Study of FCH-PET-CT in Men With Prostate Cancer and a DNA Repair Gene Mutation.
Olaparib Maintenance Monotherapy in Patients With BRCA Mutated Ovarian Cancer Following First Line Platinum Based Chemotherapy.
Polygenic Risk Scores and Multi-cancer Early Detection for Ovarian Cancer
The IMPACT Study - Identification of Men With a Genetic Predisposition to ProstAte Cancer
Low Dose TamOxifen and LifestylE Changes for bReast cANcer prevenTion
Study of SYN608 for the Treatment of Advanced or Metastatic Solid Tumors
Study of SYN818 for the Treatment of Advanced or Metastatic Solid Tumors
MEASUREMENT OF CIRCULATING MUTATION BURDEN
Prophylactic Prostatectomy for Prostate Cancer (PPPC)
Novel Neoadjuvant and Adjuvant Strategy for Germline BRCA 1/2 Mutated Triple Negative Breast Cancer
Robotic Nipple Sparing Mastectomy with Immediate Reconstruction
Tranexamic Acid Usage in Bilateral Mastectomy to Reduce Post-surgical Drainage
MiniLap Vs Standard Laparoscopy in Prophylactic Bilateral Salpingo-oophorectomy in BRCA-Mutated Patients
Intensive Adjuvant Therapy for TNBC with BRCA Gene Mutation
Clinical Outcomes of Use of Olaparib in Castration Resistant Prostate Cancer
Phase I Clinical Trials Investigating the Potential Efficacy of Axitinib in Patients With a BRCA 1/2 Mutations