Key Insights

Highlights

Success Rate

100% trial completion (above average)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 50/100

Termination Rate

0.0%

0 terminated out of 12 trials

Success Rate

100.0%

+13.5% vs benchmark

Late-Stage Pipeline

0%

0 trials in Phase 3/4

Results Transparency

25%

2 of 8 completed with results

Key Signals

2 with results100% success

Data Visualizations

Phase Distribution

9Total
Early P 1 (1)
P 1 (4)
P 2 (4)

Trial Status

Completed8
Withdrawn2
Not Yet Recruiting1
Recruiting1

Trial Success Rate

100.0%

Benchmark: 86.5%

Based on 8 completed trials

Clinical Trials (12)

Showing 12 of 12 trials
NCT07680439Phase 2Not Yet Recruiting

Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

NCT01106794Recruiting

Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem Glioma

NCT01837862Phase 1Completed

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

NCT03178032Phase 1CompletedPrimary

Oncolytic Adenovirus, DNX-2401, for Naive Diffuse Intrinsic Pontine Gliomas

NCT03355794Phase 1Completed

A Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)

NCT03666507Completed

Vegetative Monitoring During Brainstem-associated Surgery

NCT00879437Phase 2Completed

Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma

NCT01316809Phase 1Completed

AZD8055 for Adults With Recurrent Gliomas

NCT01117155Withdrawn

A Pilot Study Evaluating 18F-L-Thymidine (FLT) PET Imaging in Children With Gliomas

NCT02976441Early Phase 1Withdrawn

Autologous Stem Cell Collection and Reinfusion in Newly Diagnosed High Grade Gliomas

NCT01756989Phase 2CompletedPrimary

ANGIOCOMB Antiangiogenic Therapy for Pediatric Patients With Diffuse Brain Stem and Thalamic Tumors

NCT01118377Phase 2CompletedPrimary

A Study of Capecitabine (Xeloda®) and Concomitant Radiation Therapy in Children With Newly Diagnosed Brainstem Gliomas

Showing all 12 trials

Research Network

Activity Timeline