Bipolar Depression
190
26
32
111
Key Insights
Highlights
Success Rate
87% trial completion (above average)
Published Results
58 trials with published results (31%)
Research Maturity
111 completed trials (58% of total)
Clinical Risk Assessment
Based on trial outcomes
Low Risk
Score: 17/100
8.9%
17 terminated out of 190 trials
86.7%
+0.2% vs benchmark
33%
63 trials in Phase 3/4
52%
58 of 111 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 111 completed trials
Clinical Trials (190)
An Open-label Study of Azetukalner in Bipolar I or II Depression (X-CEED-OLE)
A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)
Task-State-Based Temporal Interference Stimulation (TI) to Improve Depression in Patients With Bipolar Disorder
Efficacy and Safety Assessment of Temporal Interference Stimulation to Improve Bipolar Depression
SYNCED - SYNChronized Eating in Bipolar Depression Study
Focused Ultrasound Amygdala Neuromodulation
Electro-Magnetic Convulsive Therapies for Depression: a Non-inferiority Study
Dopamine D3 Receptor Occupancy in Bipolar Depression
Low Field Magnetic Stimulation: Imaging Biomarkers in Geriatric Bipolar Depression
Theta-Burst Stimulation for Bipolar Depression
Empagliflozin Adjunctive Therapy in Bipolar Depression
Ketamine for Treatment-Resistant Bipolar Disorder
Maintenance Ketamine Infusions for Treatment-Resistant Bipolar Depression
Adjunctive Bright Light Therapy in Patients With Bipolar Depression and Eveningness
University of Iowa Interventional Psychiatry Service Patient Registry
PROgram To Enhance Cardiovascular Risk Trough an Intervention of Nutrition in Bipolar Disorder
Efficacy, Tolerability, and Cognitive Effects of Deep Transcranial Magnetic Stimulation for Bipolar Depression
Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder
RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE)
Braining- Aerobic Physical Activity as Add on Treatment in Bipolar Depression