Bipolar Depression
191
26
32
113
Key Insights
Highlights
Success Rate
87% trial completion (above average)
Published Results
59 trials with published results (31%)
Research Maturity
113 completed trials (59% of total)
Clinical Risk Assessment
Based on trial outcomes
Low Risk
Score: 17/100
8.9%
17 terminated out of 191 trials
86.9%
+0.3% vs benchmark
33%
63 trials in Phase 3/4
52%
59 of 113 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 113 completed trials
Clinical Trials (191)
Electro-Magnetic Convulsive Therapies for Depression: a Non-inferiority Study
Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients
Safety and Feasibility of DBS for Bipolar Depression
OSU6162 in Bipolar Depression (OBID)
An Open-label Study of Azetukalner in Bipolar I or II Depression (X-CEED-OLE)
A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)
Brexpiprazole Treatment for Bipolar I Depression
Ketogenic Intervention for Bipolar Depression
A Trial of the Fatty Acid Amide Hydrolase Inhibitor Palmitoylethanolamide in Bipolar Depression
Neurobiological Effects of Psilocybin in Treatment Resistant Bipolar Depression
EEG Microstate and Neuroinflammatory Biomarkers in Older Age Patients With Major Depressive Disorder Receiving ECT
A Pilot Study Investigating the Efficacy of Minocycline and N-Acetyl Cysteine for Bipolar Depression
Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder
Ketamine Associated ACC GABA and Glutamate Change and Depression Remission:
Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder
RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE)
Task-State-Based Temporal Interference Stimulation (TI) to Improve Depression in Patients With Bipolar Disorder
Efficacy and Safety Assessment of Temporal Interference Stimulation to Improve Bipolar Depression
SYNCED - SYNChronized Eating in Bipolar Depression Study
Focused Ultrasound Amygdala Neuromodulation