Key Insights

Highlights

Success Rate

63% trial completion

Published Results

11 trials with published results (21%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

11.5%

6 terminated out of 52 trials

Success Rate

62.5%

-24.0% vs benchmark

Late-Stage Pipeline

2%

1 trials in Phase 3/4

Results Transparency

110%

11 of 10 completed with results

Key Signals

11 with results63% success

Data Visualizations

Phase Distribution

46Total
Early P 1 (2)
P 1 (32)
P 2 (11)
P 3 (1)

Trial Status

Recruiting17
Completed10
Active Not Recruiting9
Not Yet Recruiting7
Terminated6
Unknown2

Trial Success Rate

62.5%

Benchmark: 86.5%

Based on 10 completed trials

Clinical Trials (52)

Showing 20 of 20 trials
NCT05365659Phase 1RecruitingPrimary

IKS03 in Patients With Advanced B Cell Non-Hodgkin Lymphomas

NCT07713511Not Yet Recruiting

INfections in Patients Treated With CAR-T

NCT06564038Phase 1Recruiting

A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

NCT04970901Phase 1Active Not RecruitingPrimary

A Study to Evaluate the Safety and Anti-cancer Activity of Loncastuximab Tesirine in Combination With Other Anti-cancer Agents in Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (LOTIS-7)

NCT06242834Phase 2Active Not RecruitingPrimary

Pembrolizumab and Tazemetostat to Overcome Immune Tolerance Following ASCT or CAR T-cell Therapy in Patients With Aggressive B-Cell Non-Hodgkin's Lymphoma

NCT07220616Phase 1Recruiting

A First-in-Human Trial of DS3790a in Participants With Hematological Malignancies

NCT06464185Phase 1Active Not RecruitingPrimary

A Prospective Clinical Study of CD3-CD20 Bisspecific Antibody Based Therapy Combined With CD19-CAR T Cells in the Treatment of Relapsed Refractory B-cell Non-Hodgkin Lymphoma

NCT07123454Phase 1RecruitingPrimary

A Phase I/II Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

NCT06526793Phase 2RecruitingPrimary

Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL

NCT04257578Phase 1Active Not RecruitingPrimary

Acalabrutinib and Anti-CD19 CAR T-cell Therapy for the Treatment of B-cell Lymphoma

NCT07658352Phase 1Not Yet RecruitingPrimary

A First-in-Human Study of HP-002 for Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

NCT07661537Phase 1Not Yet RecruitingPrimary

A Clinical Study of SHR-3079 in B-cell Non-Hodgkin Lymphoma

NCT03017820Phase 1RecruitingPrimary

A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma

NCT06879340Phase 1RecruitingPrimary

Evaluating the Safety and Efficacy of DuoCAR20.19.22-D95 in Adult Patients With Relapsed or Refractory B-cell Malignancies

NCT07584850Early Phase 1Not Yet RecruitingPrimary

Evaluation of GI001 for Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

NCT07097363Phase 2RecruitingPrimary

Epcoritamab With Dose Adjusted Etoposide, Cyclophosphamide, Vincristine, Doxorubicin, Prednisone and Rituximab (EPOCH-R) for the Treatment of Aggressive B-Cell Non-Hodgkin Lymphoma

NCT07480837Active Not RecruitingPrimary

Dynamic Monitoring of Plasma ctDNA for Prognostic Assessment in Patients With B-Cell Non-Hodgkin Lymphoma

NCT05432635Phase 1RecruitingPrimary

Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) Following Stem Cell Transplantation for the Treatment of Intermediate or High Grade B-cell Non-Hodgkin Lymphoma

NCT06191887Phase 1RecruitingPrimary

B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies

NCT07053670Phase 1RecruitingPrimary

A Clinical Study Exploring CT1190B in the Treatment of Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma ( CT1190B-CG11001 )

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