Key Insights

Highlights

Success Rate

75% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

9.5%

2 terminated out of 21 trials

Success Rate

75.0%

-11.5% vs benchmark

Late-Stage Pipeline

5%

1 trials in Phase 3/4

Results Transparency

100%

6 of 6 completed with results

Key Signals

6 with results75% success

Data Visualizations

Phase Distribution

20Total
Not Applicable (1)
Early P 1 (2)
P 1 (14)
P 2 (2)
P 3 (1)

Trial Status

Recruiting8
Completed6
Active Not Recruiting3
Terminated2
Unknown2

Trial Success Rate

75.0%

Benchmark: 86.5%

Based on 6 completed trials

Clinical Trials (21)

Showing 20 of 20 trials
NCT07271667Phase 2Recruiting

A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies

NCT06542250Phase 1RecruitingPrimary

A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

NCT07349849Early Phase 1RecruitingPrimary

Exploratory Study on mRNA Therapeutic Drug Targeting CD19 for the Treatment of Hematologic Malignancies

NCT01905813Phase 1Active Not RecruitingPrimary

Study of INCB040093 in Subjects With Previously Treated B-Cell Malignancies

NCT04509700Phase 2Active Not RecruitingPrimary

Rollover Study to Provide Continued Treatment for Participants With B-Cell Malignancies Previously Enrolled in Studies of Parsaclisib (INCB050465)

NCT04170283Phase 3Active Not RecruitingPrimary

Long-term Extension Study of Zanubrutinib (BGB-3111) Regimens in Participants With B-cell Malignancies

NCT03125577Phase 1RecruitingPrimary

Combination CAR-T Cell Therapy Targeting Hematological Malignancies

NCT03050190Phase 1RecruitingPrimary

A Phase I/II Multiple Center Trial of 4SCAR19 Cells in the Treatment of Relapsed and Refractory B Cell Malignancies

NCT02327078Phase 1CompletedPrimary

A Study of the Safety, Tolerability, and Efficacy of Epacadostat Administered in Combination With Nivolumab in Select Advanced Cancers (ECHO-204)

NCT07065279Not ApplicableRecruitingPrimary

JY231(JY231) Injection for the Treatment of R/R B-cell Malignancies

NCT02457598Phase 1TerminatedPrimary

Dose Escalation and Dose Expansion Study of Tirabrutinib in Combination With Other Targeted Anti-cancer Therapies in Adults With B-cell Malignancies

NCT06958679Phase 1RecruitingPrimary

Evaluation of SYS6005 in Patients With Advanced Malignant Tumor

NCT04551963Phase 1CompletedPrimary

Interaction Study of Zanubrutinib With Moderate and Strong CYP3A Inhibitors in Participants With B-Cell Malignancies

NCT05683717Phase 1RecruitingPrimary

A Phase 1 Study to Evaluate the Safety and Tolerability of TT-01488 in Patients With B-Cell Malignancies

NCT02018861Phase 1CompletedPrimary

A Phase 1/2, Open-Label, Dose Escalation, Safety and Tolerability Study of INCB050465 and Itacitinib in Subjects With Previously Treated B-Cell Malignancies (CITADEL-101)

NCT05275504Phase 1UnknownPrimary

Study to Evaluate the Safety and Tolerability of TT-01488 in Patients With B-Cell Malignancies

NCT02343120Phase 1CompletedPrimary

Study of the Safety and Pharmacokinetics of BGB-3111 in Subjects With B-Cell Lymphoid Malignancies

NCT00983619Phase 1CompletedPrimary

A Clinical Study Using MEDI-551 in Adult Participants With Relapsed or Refractory Advanced B-Cell Malignancies

NCT03701438TerminatedPrimary

Immune Response to Influenza Vaccine in Adults With B-cell Malignancies Treated With Idelalisib

NCT03642496Early Phase 1UnknownPrimary

Clinical Study of ET019002-T Cell Therapy for Refractory/Relapsed B-Cell Malignancies

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