Key Insights

Highlights

Success Rate

78% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

9.5%

2 terminated out of 21 trials

Success Rate

77.8%

-8.8% vs benchmark

Late-Stage Pipeline

5%

1 trials in Phase 3/4

Results Transparency

86%

6 of 7 completed with results

Key Signals

6 with results78% success

Data Visualizations

Phase Distribution

20Total
Not Applicable (1)
Early P 1 (2)
P 1 (14)
P 2 (2)
P 3 (1)

Trial Status

Recruiting8
Completed7
Unknown2
Terminated2
Active Not Recruiting2

Trial Success Rate

77.8%

Benchmark: 86.5%

Based on 7 completed trials

Clinical Trials (21)

Showing 20 of 20 trials
NCT06542250Phase 1RecruitingPrimary

A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

NCT04509700Phase 2Active Not RecruitingPrimary

Rollover Study to Provide Continued Treatment for Participants With B-Cell Malignancies Previously Enrolled in Studies of Parsaclisib (INCB050465)

NCT03050190Phase 1RecruitingPrimary

A Phase I/II Multiple Center Trial of 4SCAR19 Cells in the Treatment of Relapsed and Refractory B Cell Malignancies

NCT03125577Phase 1RecruitingPrimary

Combination CAR-T Cell Therapy Targeting Hematological Malignancies

NCT07271667Phase 2Recruiting

A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies

NCT01905813Phase 1CompletedPrimary

Study of INCB040093 in Subjects With Previously Treated B-Cell Malignancies

NCT07349849Early Phase 1RecruitingPrimary

Exploratory Study on mRNA Therapeutic Drug Targeting CD19 for the Treatment of Hematologic Malignancies

NCT04170283Phase 3Active Not RecruitingPrimary

Long-term Extension Study of Zanubrutinib (BGB-3111) Regimens in Participants With B-cell Malignancies

NCT02327078Phase 1CompletedPrimary

A Study of the Safety, Tolerability, and Efficacy of Epacadostat Administered in Combination With Nivolumab in Select Advanced Cancers (ECHO-204)

NCT07065279Not ApplicableRecruitingPrimary

JY231(JY231) Injection for the Treatment of R/R B-cell Malignancies

NCT02457598Phase 1TerminatedPrimary

Dose Escalation and Dose Expansion Study of Tirabrutinib in Combination With Other Targeted Anti-cancer Therapies in Adults With B-cell Malignancies

NCT06958679Phase 1RecruitingPrimary

Evaluation of SYS6005 in Patients With Advanced Malignant Tumor

NCT04551963Phase 1CompletedPrimary

Interaction Study of Zanubrutinib With Moderate and Strong CYP3A Inhibitors in Participants With B-Cell Malignancies

NCT05683717Phase 1RecruitingPrimary

A Phase 1 Study to Evaluate the Safety and Tolerability of TT-01488 in Patients With B-Cell Malignancies

NCT02018861Phase 1CompletedPrimary

A Phase 1/2, Open-Label, Dose Escalation, Safety and Tolerability Study of INCB050465 and Itacitinib in Subjects With Previously Treated B-Cell Malignancies (CITADEL-101)

NCT05275504Phase 1UnknownPrimary

Study to Evaluate the Safety and Tolerability of TT-01488 in Patients With B-Cell Malignancies

NCT02343120Phase 1CompletedPrimary

Study of the Safety and Pharmacokinetics of BGB-3111 in Subjects With B-Cell Lymphoid Malignancies

NCT00983619Phase 1CompletedPrimary

A Clinical Study Using MEDI-551 in Adult Participants With Relapsed or Refractory Advanced B-Cell Malignancies

NCT03701438TerminatedPrimary

Immune Response to Influenza Vaccine in Adults With B-cell Malignancies Treated With Idelalisib

NCT03642496Early Phase 1UnknownPrimary

Clinical Study of ET019002-T Cell Therapy for Refractory/Relapsed B-Cell Malignancies

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